The Effect of Immunotherapy Treatment on Leukaemia Growth Dynamic Model

DOI

10.2991/aer.k.211215.083How to use a DOI?

Keywords

Immunotherapy treatment; Dynamics of leukaemia growth; Mathematical model

Abstract

Cancer is one of the leading causes of death globally, claiming ten million lives in 2020. Leukaemia, also known as blood cancer, is a condition in which the growth of white blood cells occurs uncontrollably. This study aims to simulate the mathematical model for the dynamics of leukaemia growth. The simulation shows that when immunotherapy is not present (B = 0), the number of infected and cancer cells is massive. As immunotherapy is applied and present (B > 0), the concentration of immune cells surges in the blood therefore the number of infected cells and cancer cells declines because the external re-infusion rate of immune cells increases in the blood, and the number of infected cells decreases due to the interaction between cancer cells and immune cells.

Copyright

© 2021 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Dimas A. Maulana
AU  - Yusuf Fuad
AU  - Ayunin Sofro
AU  - Hery T. Sutanto
AU  - Evitia N. Septy
PY  - 2021
DA  - 2021/12/16
TI  - The Effect of Immunotherapy Treatment on Leukaemia Growth Dynamic Model
BT  - Proceedings of the International Joint Conference on Science and Engineering 2021 (IJCSE 2021)
PB  - Atlantis Press
SP  - 492
EP  - 497
SN  - 2352-5401
UR  - https://doi.org/10.2991/aer.k.211215.083
DO  - 10.2991/aer.k.211215.083
ID  - Maulana2021
ER  -