Synthesis of Micro-nanostructured TiO2 Sphere with Homogeneous Precipitation assisted by MicrowaveIrradiation and its Drug Loading Capacity

DOI

10.2991/ifeesm-17.2018.79How to use a DOI?

Keywords

TiO2; Homogeneous Precipitation; Microwave irradiation; Sorafenib.

Abstract

Nanoparticulate titanium dioxide were synthesized via homogeneous precipitation assisted by microwave irradiation.The powder was characterized by X-ray diffraction(XRD), Scanning Electron Microscopy(SEM), Differential scanning calorimetryand thermogravimetric analysis(TG-DSC), Roman spectra and Transmission electron microscopy(TEM). The results showed that obtained TiO2 were pure-phase anatase with BET Surface Area of 53.9445m²/g and the average pore diameter of 9.3439nmand 800°C is the crystal phase transformation temperature, exhibited high drug loading capacity towards sorafenib of 5.65% while the TiO2/sorafenib ratio at 15:5 for 6h under stirring condition. Micro-nanostructured TiO2, as a drug delivery system, has great potential in the treatment of cancer diseases.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Di Liu
AU  - Shi-Ting Deng
AU  - Hong Yu
AU  - Yong-Guang Bi
PY  - 2018/02
DA  - 2018/02
TI  - Synthesis of Micro-nanostructured TiO2 Sphere with Homogeneous Precipitation assisted by MicrowaveIrradiation and its Drug Loading Capacity
BT  - Proceedings of the 2017 3rd International Forum on Energy, Environment Science and Materials (IFEESM 2017)
PB  - Atlantis Press
SP  - 421
EP  - 424
SN  - 2352-5401
UR  - https://doi.org/10.2991/ifeesm-17.2018.79
DO  - 10.2991/ifeesm-17.2018.79
ID  - Liu2018/02
ER  -