Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)

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Biochemical Changes of Liver and KidneyAfter Bone Graft Implant from Black Devil Snail (Faunus ater) Shell Material

Authors
Erwin Erwin, T. Fadrial Karmil, Teuku Zahrial Helmi, Nuzul Asmilia, Muhammad Isa, Wahyu Eka Sari, Budianto Panjaitan, Sugito, Hathalia Y. Utari, Azzalia N. Diva, Astri Wulandari
Corresponding Author
Erwin Erwin
Available Online 21 April 2021.
DOI
10.2991/absr.k.210420.007How to use a DOI?
Keywords
SGOT, SGPT, Creatinine, Faunus ater
Abstract

Biochemical changes in blood can be used as an indicator in liver and kidney disorder. This study aims to discover the changes of serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), creatinine and blood urea nitrogen (BUN) levels after the implant of black devil snail shell powder in rabbits. This study used 6 male rabbits, aged 6-8 months and weighted 1.5-2 kg which were divided into 2 groups. Surgical procedure was done sterile and aseptically by creating defect in the left area of femur diaphysis with the size of 0.5 mm2 and depth reached to canalis medullaris. Group 1 (G1) was not implanted and left to heal on its own, while group 2 (G2) was implanted with 0.25 g of black devil snail shell powder. Blood sample was withdrawn from auricular vein in day 0 before surgery, and day 7, 14, 28, 56 after surgery. The SGOT and SGPT level increased in day 7 after surgery and were significantly different between groups. The BUN level increased in day 14 after surgery, while creatinine increased in day 7 with no significant differences found between groups. The biochemical changes of liver and kidney is still in its normal range, so cue shell powder has the potential to be developed as natural hydroxyapatite.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)
Series
Advances in Biological Sciences Research
Publication Date
21 April 2021
ISBN
978-94-6239-367-7
ISSN
2468-5747
DOI
10.2991/absr.k.210420.007How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Erwin Erwin
AU  - T. Fadrial Karmil
AU  - Teuku Zahrial Helmi
AU  - Nuzul Asmilia
AU  - Muhammad Isa
AU  - Wahyu Eka Sari
AU  - Budianto Panjaitan
AU  - Sugito
AU  - Hathalia Y. Utari
AU  - Azzalia N. Diva
AU  - Astri Wulandari
PY  - 2021
DA  - 2021/04/21
TI  - Biochemical Changes of Liver and KidneyAfter Bone Graft Implant from Black Devil Snail (Faunus ater) Shell Material
BT  - Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)
PB  - Atlantis Press
SP  - 29
EP  - 34
SN  - 2468-5747
UR  - https://doi.org/10.2991/absr.k.210420.007
DO  - 10.2991/absr.k.210420.007
ID  - Erwin2021
ER  -