Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)

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The Prominent Role of Pituitary Adenylate Cyclase-Activating Polypeptide in Spermatogenesis and Function of Spermatozoa: A Mini Review

Authors
Muslim Akmal, Zulkarnain, Gholib Gholib, Teuku Zahrial Helmi, Sugito
Corresponding Author
Muslim Akmal
Available Online 21 April 2021.
DOI
10.2991/absr.k.210420.029How to use a DOI?
Keywords
pituitary adenylate cyclase-activating polypeptide, reproduction, spermatogenesis, male fertility
Abstract

Spermatogenesis is a great, complex, and long process. This process take place in the tubulus seminiferus of the testis and consists of three phases i.e. proliferation, meiosis, and spermiogenesis. In proliferation phase, the number of cells were multiplied, while in the meiosis occurs the completion of cleavage to form haploid cells. In the spermiogenesis, the cells perform a morphological change to form the mature gamet that is spermatozoa. Spermatogenesis involves the role of hormones and many molecules resulting the functional spermatozoa which crucial to induce the process of fertilization. Pituitary adenylate cyclase-activating polypeptide (PACAP) is an elderly and multifunctional molecule that necessary in spermatogenesis and the quality of spermatozoa. Many results revealed that PACAP molecule is responsible for male reproduction and fertility. The main objective of this review is to describe the prominent role of PACAP in spermatogenesis and the spermatozoa function.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)
Series
Advances in Biological Sciences Research
Publication Date
21 April 2021
ISBN
978-94-6239-367-7
ISSN
2468-5747
DOI
10.2991/absr.k.210420.029How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Muslim Akmal
AU  - Zulkarnain
AU  - Gholib Gholib
AU  - Teuku Zahrial Helmi
AU  - Sugito
PY  - 2021
DA  - 2021/04/21
TI  - The Prominent Role of Pituitary Adenylate Cyclase-Activating Polypeptide in Spermatogenesis and Function of Spermatozoa: A Mini Review
BT  - Proceedings of the 2nd International Conference on Veterinary, Animal, and Environmental Sciences (ICVAES 2020)
PB  - Atlantis Press
SP  - 136
EP  - 141
SN  - 2468-5747
UR  - https://doi.org/10.2991/absr.k.210420.029
DO  - 10.2991/absr.k.210420.029
ID  - Akmal2021
ER  -