Proceedings of the 2nd International Conference on Science, Technology, and Modern Society (ICSTMS 2020)

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The Potency of Legetan warak (Adenostemma lavenia) and Kersen Leaf (Muntingia calabura) Extract as a Candidate for Chronic Obstructive Pulmonary Disease (COPD) Herbal Medicine

Authors
Dyah Iswantini, Bagaskoro Tuwalaid, Trivadila
Corresponding Author
Dyah Iswantini
Available Online 11 September 2021.
DOI
10.2991/assehr.k.210909.097How to use a DOI?
Keywords
Anti-inflammatory, Chronic Obstructive Pulmonary Disease (COPD), Cyclooxygenase-2 (COX-2), Adenostemma lavenia, Muntingia calabura
Abstract

Lung inflammation is a normal response in COPD patients that are usually treated using anti-inflammatory drugs. Most anti-inflammatory drugs work to inhibit the activity of cyclooxygenase which produces inflammatory mediators. This study aims to examine the anti-inflammatory potency of legetan warak (Adenostemma lavenia) and kersen leaf (Muntingia calabura) extract for treating COPD through inhibition of Cyclooxygenase-2 (COX-2) and to predict the chemical compounds that play a role in it through laboratory tests and literature studies. Phytochemical assays show that both legetan warak and kersen leaf contain flavonoid compounds. Based on some literature studies, it is concluded that the extract of legetan warak and kersen leaf have the potency as an anti-inflammatory by inhibiting COX-2 activity. The compounds that assumed to be COX-2 inhibit are certain compounds from flavonoid and phenolic compounds groups.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd International Conference on Science, Technology, and Modern Society (ICSTMS 2020)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
11 September 2021
ISBN
978-94-6239-426-1
ISSN
2352-5398
DOI
10.2991/assehr.k.210909.097How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Dyah Iswantini
AU  - Bagaskoro Tuwalaid
AU  - Trivadila
PY  - 2021
DA  - 2021/09/11
TI  - The Potency of Legetan warak (Adenostemma lavenia) and Kersen Leaf (Muntingia calabura) Extract as a Candidate for Chronic Obstructive Pulmonary Disease (COPD) Herbal Medicine
BT  - Proceedings of the 2nd International Conference on Science, Technology, and Modern Society (ICSTMS 2020)
PB  - Atlantis Press
SP  - 447
EP  - 452
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.210909.097
DO  - 10.2991/assehr.k.210909.097
ID  - Iswantini2021
ER  -