Fabrication of PLGA/ (HA/CS) n/CD34 Bioactive Multiplayer Film on Stainless Steel Stent

DOI

10.2991/icsste-15.2015.219How to use a DOI?

Keywords

Electrostatic self-assembly; multilayer films; CD34 antibody; Polylactide-co-glycolide (PLGA)

Abstract

At present PLGA is widely used in clinical as a drug carrier in drug-eluting stent coating. But due to the existence of poor biological activity and easily cased thrombosis of PLGA, it is serious to increase the biological activity and hemocompatibility of drug-eluting stent. In this research, the paper try to fabricate PLGA/ (HA/CS) n/CD34 bioactive multilayer films on biomedical 316L stainless steel (316LSS) surface via electrostatic self-assembly. Using fluorescent dyes to make the characterization of the films. It is considered the effect of corrosion resistance in blood about solution concentration and layers of multilayer films through blood washed simulation experiments. The research makes platelet adhesion experiment on multilayer films in different solution concentration and layers in order to optimize process parameters.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - Li Ying
AU  - Zhao Hong
AU  - Zhang Shixuan
PY  - 2015/04
DA  - 2015/04
TI  - Fabrication of PLGA/ (HA/CS) n/CD34 Bioactive Multiplayer Film on Stainless Steel Stent
BT  - Proceedings of the 2015 International Conference on Social Science and Technology Education
PB  - Atlantis Press
SP  - 866
EP  - 869
SN  - 2352-5398
UR  - https://doi.org/10.2991/icsste-15.2015.219
DO  - 10.2991/icsste-15.2015.219
ID  - Ying2015/04
ER  -