Reaction Order Parameters of Erythrocyte Sedimentation Rate, Neutrophil-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio as Markers for Colorectal Carcinoma After Chemotherapy
- DOI
- 10.2991/assehr.k.210305.062How to use a DOI?
- Keywords
- Colorectal cancer (CRC) Biomarker, erythrocyte sedimentation rate, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio
- Abstract
Colorectal Cancer (CRC) ranks 3rd highest cancer incidence, so it is a serious health problem in Indonesia. A new erythrocyte sedimentation rate method was developed to determine a biomarker for CRC. This study aims to investigate reaction order parameters of erythrocyte sedimentation rate (ESR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) as markers for colorectal carcinoma after chemotherapy. One ml blood was collected from 49 subjects by venipuncture, which then drawn for Westergren analysis. The ESR was measured every minute for 2 hours. The parameter-1 and parameter-2 reaction order of the two groups of research subjects were determined from ESR linear equation. The respective values of parameter-1, parameter-2, NLR, and PLR from normal group and CRC group were compared by t test. The results showed that the parameters of reaction order, NLR, and PLR have good performance to be used as markers for CRC after chemotherapy.
- Copyright
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Ngadikun AU - Untung Widodo AU - Agus Barmawi AU - Ahmad Hamim AU - Kuncoro Asih Nugroho AU - Iska Rahman Kurniawan AU - Metamalik Pasala AU - Izzati Amayazifun Khalifa Farzana PY - 2021 DA - 2021/03/08 TI - Reaction Order Parameters of Erythrocyte Sedimentation Rate, Neutrophil-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio as Markers for Colorectal Carcinoma After Chemotherapy BT - Proceedings of the 7th International Conference on Research, Implementation, and Education of Mathematics and Sciences (ICRIEMS 2020) PB - Atlantis Press SP - 427 EP - 433 SN - 2352-5398 UR - https://doi.org/10.2991/assehr.k.210305.062 DO - 10.2991/assehr.k.210305.062 ID - 2021 ER -