Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017)

Immunomodulation Effect of Meniran (Phyllanthus niruri linn) on Blood Profile of Broiler Chickens Infected with Enterotoxin of Antibiotic-Resistant Escherichia coli

Authors
Retno Sri Wahjuni, Emy Koestanti Sabdoningrum, Sri Hidanah
Corresponding Author
Retno Sri Wahjuni
Available Online August 2017.
DOI
10.2991/icpsuas-17.2018.66How to use a DOI?
Keywords
Immunomodulation, Phyllanthus niruri Linn.extract, Broiler, Escherichia coli
Abstract

The use of antibiotics against Escherichia coli on broiler chicken should be re-evaluated because antibiotic-resistant Escherichia coli has found. Meniran ( Phyllanthus niruri Linn ) is a plant that can be used as an alternative to prevention and treatment of the diseases caused by Escherichia coli enterotoxin. In this study, broiler chickens about 21 days of age were divided into six groups. Group 1 was positive control infected by Escherichia coli while group 2 was negative control without infection. The next three group were infected by Escherichia coli and given the extract of meniran with several different doses including 20%, 25%, and 30%, respectively, and in the last group only used an antibiotic as a treatment. Blood sample collection was conducted on five days after treatment. The data obtained were analyzed using ANOVA and was continued by Duncan Multiple Range Test. The results showed that there was a significant difference of immunomodulation activity in the group with 30% doses of meniran's extract. The 30% doses of menirans'e extract are able to reduce the amount of lymphocytes in the blood. In conclusion, the extract of meniran can be used as immunomodulation to Escherichia coli at 30% of doses.

Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

Cite this article

TY  - CONF
AU  - Retno Sri Wahjuni
AU  - Emy Koestanti Sabdoningrum
AU  - Sri Hidanah
PY  - 2017/08
DA  - 2017/08
TI  - Immunomodulation Effect of Meniran (Phyllanthus niruri linn) on Blood Profile of Broiler Chickens Infected with Enterotoxin of Antibiotic-Resistant Escherichia coli
BT  - Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017)
PB  - Atlantis Press
SP  - 311
EP  - 313
SN  - 2352-5398
UR  - https://doi.org/10.2991/icpsuas-17.2018.66
DO  - 10.2991/icpsuas-17.2018.66
ID  - SriWahjuni2017/08
ER  -