Analysis on the Treatment of Gray Matter Heterotopia Epilepsy

DOI

10.2991/assehr.k.220110.162How to use a DOI?

Keywords

Gray matter heterotopia; Epilepsy; Pathophysiology; Molecular mechanism

Abstract

This essay started off by giving a brief introduction about gray matter heterotopia and its classification. It is then followed by listing out the common genetic mutations that is associated with the disease including FLNA, ARFGEF2, C6orf70, FAT4, DCSH1 for periventricular nodular heterotopia (PNH), and DCX, LIS1, TUBA1A, TUBG1 for subcortical band heterotopia (SBH). Upon reviewing various literature, credible evidence regarding the possible molecular mechanism of the mutations were summarized as well. Due to the high prevalence of epilepsy involved with the disease, evidence regarding the pathophysiology of seizures were also discussed. Clinical aspects of the disorder including signs and symptoms, imaging findings leading to diagnosis, and management strategies were also highlighted.

Copyright

© 2022 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Lixiongyu Xiong
PY  - 2022
DA  - 2022/01/28
TI  - Analysis on the Treatment of Gray Matter Heterotopia Epilepsy
BT  - Proceedings of the 2021 International Conference on Public Art and Human Development ( ICPAHD 2021)
PB  - Atlantis Press
SP  - 858
EP  - 863
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.220110.162
DO  - 10.2991/assehr.k.220110.162
ID  - Xiong2022
ER  -