Research on the Growth of Breast Tumor

DOI

10.2991/assehr.k.220110.081How to use a DOI?

Keywords

Breast tumor; CoMPas; Primary tumor (PT); Secondary distant metastatic tumor (MTS); Exponential/Linear model

Abstract

Malignant breast tumor or cancer is notorious for its rampant spread over to any other parts of body and can be potentially a fatal disease. Many theoretical studies on the growth kinetics of breast tumor have been carried out in order to generalize the fundamental characteristic of it. This knowledge, in turn, can then be applied to actual clinical practice to give prediction as early as possible. The CoMPaS model is such a theoretical tool to predict when and how the tumor volume may develop. It handles the primary tumor and the secondary distant metastatic tumor simultaneously, and applies exponential as well as approximate linear dynamics to describe the growth of tumors even when they are still in the nonvisible stage, so it is helpful to meet the goal “find early, save early”. In this paper, we make efforts to understand the details of CoMPaS model. The underlying equations are first introduced and derived, then one typical solution is given. The original paper seems to ignore the linear growth and keep only the exponential one, which contradicts the experiment fact, so we come up with a remedy assumption that the linear growth is switched on very lately, then our results match well those from the original paper. The issue should be raised here is when the linear growth comes into play.

Copyright

© 2022 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Jinrui Huang
PY  - 2022
DA  - 2022/01/28
TI  - Research on the Growth of Breast Tumor
BT  - Proceedings of the 2021 International Conference on Public Art and Human Development ( ICPAHD 2021)
PB  - Atlantis Press
SP  - 414
EP  - 418
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.220110.081
DO  - 10.2991/assehr.k.220110.081
ID  - Huang2022
ER  -