Effects of Serum Cystatin C Levels on Increased Systolic and Diastolic Blood Pressure in the Elderly With Normal Renal Function

DOI

10.2991/ahsr.k.210115.009How to use a DOI?

Keywords

Cystatin C, Systolic blood pressure, Diastolic blood pressure, Elderly, Normal renal function

Abstract

Increased systolic and diastolic blood pressure is a result of the process of blood vessel degeneration that often occurs in the elderly. A number of previous studies have shown that cystatin C is a strong predictor of cardiovascular and mortality risk in elderly individuals though the mechanism remains unclear. Cystatin C also increases in individuals with decreased renal function. The objective of this study was to determine the effects of serum cystatin C levels on the systolic and diastolic blood pressure of the elderly with normal renal function. This was an analytical observational study with a cross-sectional design. The subjects of this study were both men and women aged ≥60 years old without renal function impairment. The subjects underwent systolic and diastolic blood pressure measurements, and their venous blood was taken to check the levels of serum cystatin C. The data were analyzed using a fischer exact test. Involving 40 elderly subjects, this study found that the mean systolic blood pressure was 147.750±23.258 mmHg, and the mean diastolic blood pressure was 88.250±11.353 mmHg while the mean level of serum cystatin C was 1.106± 0.006 mg/l. The statistical analysis showed a significant relationship between the levels of serum cystatin C and the systolic (p=0.030, RR=1.431, 95% CI: 0.983-2.275) and diastolic blood pressure (p=0.000, RR=1.290, 95% CI: 0.515-12.076). In conclusion, elevated serum cystatin C levels were associated with increased systolic and diastolic blood pressure in elderly people with normal renal function.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - Erlina Marfianti
AU  - Auliya Nisa
PY  - 2021
DA  - 2021/01/16
TI  - Effects of Serum Cystatin C Levels on Increased Systolic and Diastolic Blood Pressure in the Elderly With Normal Renal Function
BT  - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
PB  - Atlantis Press
SP  - 43
EP  - 47
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210115.009
DO  - 10.2991/ahsr.k.210115.009
ID  - Marfianti2021
ER  -