In Vitro Study of Kaempferia galanga L. Compound, δ- 3-Carene, Against 5-Lipoxygenase

DOI

10.2991/ahsr.k.210115.088How to use a DOI?

Keywords

Kaempferia galanga, Anti-inflammatory, lipoxygenase, δ-3-carene

Abstract

Kaempferia galanga has anti-inflammatory activity and worth developing as lipoxygenase inhibitors. The aim of this study was to determined δ-3-carene, one of the potential compounds of K. galanga, as a lipoxygenase inhibitor. The LOX-inhibitor activity was tested in-vitro. The result showed that the IC50 of δ-3-carene was 23.10 µM, which was less potential compare to zileuton (7.54 µM). The study showed that K. galanga contains possible active components that could be developed as 5-LOX-inhibitor.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Lusi Putri Dwita
AU  - Supandi
AU  - Yeni
PY  - 2021
DA  - 2021/01/16
TI  - In Vitro Study of Kaempferia galanga L. Compound, δ- 3-Carene, Against 5-Lipoxygenase
BT  - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
PB  - Atlantis Press
SP  - 443
EP  - 444
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210115.088
DO  - 10.2991/ahsr.k.210115.088
ID  - Dwita2021
ER  -