Antidiabetic Effect Test of Combination of Ginger (Zingiber officinale), Lemongrass (Cymbopogon citratus), and Cinnamon (Cinnamomum verum) on Male Mice (Mus musculus)

DOI

10.2991/978-94-6463-018-3_9How to use a DOI?

Keywords

Antidiabetic; Stew; Ginger; Lemongrass; Cinnamon

Abstract

Diabetes mellitus (DM) or diabetes is a disease caused by disorders related to the hormone insulin. Ginger, lemongrass and cinnamon are traditional plants that have the potential to be developed as herbal medicines. The combination of these traditional plants can be used as an alternative treatment for diabetes mellitus. Infusions of ginger, lemongrass and cinnamon contain secondary metabolites, namely flavonoids, terpenoids and tannins. These three active compounds have antioxidant, antidiabetic, and anti-inflammatory activities. The aim of this study was to determine the antidiabetic effect of the infusion of a combination of JSKM (ginger (Zingiber officinale), lemongrass (Cymbopogon citratus) and cinnamon (Cinnamomum verum)) on male mice (Mus Musculus). The design of this research is experimental with data analysis method using SPSS 16.0. Observation of healing time is done by observing the decrease in blood sugar levels for 7 days. In this study, 5 treatment groups were used, namely the negative control group (aquadest), the positive control group (glibenclamide), the P1 dose (162 mg/kgBW), the P2 dose (324 mg/kgBW), and the P3 dose (486 mg/kgBW). The most effective dose of the antidiabetic effect of JSKM infusion in male mice was in the P3 group with a dose of 486 mg mg/kgBW.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Ni Putu Natasya Dewanti
AU  - Ajeng Dian Pertiwi
AU  - Evi Fatmi Utami
AU  - Sri Idawati
AU  - Adriyan Suhada
AU  - Nadiatul Azra Ahmad Mazlan
AU  - En Purmafitriah
PY  - 2022
DA  - 2022/12/15
TI  - Antidiabetic Effect Test of Combination of Ginger (Zingiber officinale), Lemongrass (Cymbopogon citratus), and Cinnamon (Cinnamomum verum) on Male Mice (Mus musculus)
BT  - Proceedings of the First International Conference on Medical Technology (ICoMTech 2021)
PB  - Atlantis Press
SP  - 62
EP  - 68
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-018-3_9
DO  - 10.2991/978-94-6463-018-3_9
ID  - Dewanti2022
ER  -