Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)

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Circan: A Database of Circular RNAs Exploring Chromosomal Linkages in Human Cancers

Authors
Gaurav Kumar Bhagat1, *
1Department of Biochemistry and Biophysics, University of Kalyani, Nadia, West Bengal, 741235, India
*Corresponding author. Email: gauravbcbp22@klyuniv.ac.in Email: gbnitdgp@yahoo.co.in
Corresponding Author
Gaurav Kumar Bhagat
Available Online 22 December 2022.
DOI
10.2991/978-94-6463-062-6_7How to use a DOI?
Keywords
Cancer; Chromosome; CircRNA; Database
Abstract

Circular RNAs (circRNAs) represent a milieu of non-coding RNAs that play a major role in gene regulation, development, and carcinogenesis. Circan is a database of cancer associated circular RNAs. As the interest in circRNA increases, Circan provides a systematic annotation of circRNA dysregulation in cancer and a helpful asset for studying their prominent role in cancer. Circan acts as a functional resource to efficiently browse and search various circRNAs and their annotations. This work includes circRNA name associated with each cancer subtype, gene, location of the circRNA on the chromosome, genomic length, spliced length, the PubMed reference, nucleotide sequence of each circRNA, sample description, experimental method, expression pattern, genomic context and miRNAs involved in cancer progression. On data analysis, it was seen that lesser number of cancers causing circRNAs were present on chromosomes 13, 21, 22, X, Y whereas more number were found on chromosomes 1, 2, 3, 6, 11 which might indicate the favored location of cancer causing circRNAs on the genome. As the interest in circRNAs keeps on increasing, the database will improve our knowledge of circRNA dysregulation. The URL is http://bhagatjeeesolutions.com/Cancer_circRNA.aspx

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
Series
Advances in Biological Sciences Research
Publication Date
22 December 2022
ISBN
978-94-6463-062-6
ISSN
2468-5747
DOI
10.2991/978-94-6463-062-6_7How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Gaurav Kumar Bhagat
PY  - 2022
DA  - 2022/12/22
TI  - Circan: A Database of Circular RNAs Exploring Chromosomal Linkages in Human Cancers
BT  - Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
PB  - Atlantis Press
SP  - 65
EP  - 71
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-062-6_7
DO  - 10.2991/978-94-6463-062-6_7
ID  - Bhagat2022
ER  -