Antihyperlipidemia Effects of Jengkol Leaf Extract (Archidendron jiringa)

DOI

10.2991/assehr.k.210415.021How to use a DOI?

Keywords

Jengkol leaves, Archidendron jiringa, antihyperlipidemia, propylthiouracil

Abstract

This Jengkol is one of the native plants in Indonesia. Jengkol beans are known as a popular food ingredient, and empirically the leaf is also used by people to treat hyperlipidemia. This study aimed to determine the antihyperlipidemic effect of Jengkol leaf extract (Achidendron jiringa) on male white rats induced by propylthiouracil and High fat diet. This was an experimental research with complete random design. Animals were divided into 5 groups: negative control group (tween 80), positive control (simvastatin 10 mg/kg BW), 3 other groups were given Jengkol leaf extract a dose of 100, 200, and 400 mg/kg BW. The result showed that there is a significant decline in total cholesterol levels after being given Jengkol leaf extract for 14 days at each dose respectively compared to the hyperlipidemic group. The percentages were 41.45%, 47.76%, 44.91%, and the simvastatin group was 56.70%. The study also revealed the optimal dose of Jengkol leaf extract that was 200 mg/kg BW

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Ade Arinia Rasyad
AU  - Ensiwi Munarsih
AU  - Fadilah Safitri
PY  - 2021
DA  - 2021/04/19
TI  - Antihyperlipidemia Effects of Jengkol Leaf Extract (Archidendron jiringa)
BT  - Proceedings of the First International Conference on Health, Social Sciences and Technology (ICoHSST 2020)
PB  - Atlantis Press
SP  - 92
EP  - 95
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.210415.021
DO  - 10.2991/assehr.k.210415.021
ID  - Rasyad2021
ER  -