Proceedings of the 6th International Conference of Health Polytechnic Surabaya (ICoHPS 2023)

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A Comparative Analysis of D-Dimer and Interleukin-6 Levels in COVID-19 Survivors: Implications for Long-term Outcomes

Authors
Anik Handayati1, *, Jusak Nugraha2, Rahajoe Imam Santosa3
1Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, Surabaya, Indonesia
2Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga Surabaya, Surabaya, Indonesia
3School of Medicine, Universitas Ciputra Surabaya, Surabaya, Indonesia
*Corresponding author. Email: anik_handayati@poltekkesdepkes-sby.ac.id
Corresponding Author
Anik Handayati
Available Online 23 December 2023.
DOI
10.2991/978-94-6463-324-5_3How to use a DOI?
Keywords
Prosthetic Hand; Machine Learning; Pattern Recognition; EMG
Abstract

Several studies have investigated the association between D-Dimer and Interleukin-6 levels in COVID-19 patients. Nikkhoo et al. conducted a longitudinal prospective cohort study to investigate the association between IL-6 levels and disease severity among COVID-19 patients. They found that elevated IL-6 levels were associated with increased disease severity and mortality. Huang et al. investigated the association between D-Dimer levels and disease severity among COVID-19 patients using a retrospective cohort design. They found that elevated D-Dimer levels were associated with increased disease severity, mortality, and thrombotic events. A systematic review and meta-analysis by Lippi et al. investigated the relationship between D-Dimer and Interleukin-6 levels in COVID-19 patients. They found that both biomarkers were significantly elevated in COVID-19 patients compared to healthy controls. Moreover, they found that D-Dimer levels were significantly higher in severe COVID-19 patients compared to non-severe patients. Similarly, IL-6 levels were significantly higher in severe COVID-19 patients compared to non-severe patients. Few studies have investigated the longitudinal changes in D-Dimer and Interleukin-6 levels in COVID-19 survivors. Nikkhoo et al. found that IL-6 levels decreased over time in COVID-19 survivors. However, it is unclear how D-Dimer levels evolve in COVID-19 survivors over time. The findings from these studies have several implications for long-term outcomes of COVID-19. Firstly, monitoring D-Dimer and Interleukin-6 levels may aid in assessing disease progression and response to treatment. Second, studying these biomarkers could contribute to the development of targeted therapies for COVID-19 survivors.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 6th International Conference of Health Polytechnic Surabaya (ICoHPS 2023)
Series
Advances in Health Sciences Research
Publication Date
23 December 2023
ISBN
978-94-6463-324-5
ISSN
2468-5739
DOI
10.2991/978-94-6463-324-5_3How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Anik Handayati
AU  - Jusak Nugraha
AU  - Rahajoe Imam Santosa
PY  - 2023
DA  - 2023/12/23
TI  - A Comparative Analysis of D-Dimer and Interleukin-6 Levels in COVID-19 Survivors: Implications for Long-term Outcomes
BT  - Proceedings of the 6th International Conference of Health Polytechnic Surabaya (ICoHPS 2023)
PB  - Atlantis Press
SP  - 14
EP  - 22
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-324-5_3
DO  - 10.2991/978-94-6463-324-5_3
ID  - Handayati2023
ER  -