Antibacterial Activities and Interactions Study of Ternary Lanthanide Schiff Base and Nitrogen-heterocyclic Complexes Bind to DNA
Authors
Yan-Fang Zhao, Jing-Jing Li, Yong-Liang Zhao
Corresponding Author
Yan-Fang Zhao
Available Online December 2015.
- DOI
- 10.2991/icmmcce-15.2015.192How to use a DOI?
- Keywords
- rare earth complexes; ct-DNA; fluorescence quenching; antibacterial activity
- Abstract
In this work, a series of ternary rare earth complexes were synthesized with salicylidene glycine schiff base (Sal-GlyK) as anion ligand and 2,2'-bipyridine (bipy), l, 10-phenanthroline (phen) as neutral ligand. The antibacterial activities and interactions between calf thymus DNA (ct-DNA) in Tris-HCl (pH=7.1) and the complexes were investigated by UV-Vis spectrophotometry, fluorescence quench experiment and viscosity measurement. The antibacterial activities of the complexes are all better than the ligands, and the complexes with the bigger planarity ligands are better than the small one.
- Copyright
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Yan-Fang Zhao AU - Jing-Jing Li AU - Yong-Liang Zhao PY - 2015/12 DA - 2015/12 TI - Antibacterial Activities and Interactions Study of Ternary Lanthanide Schiff Base and Nitrogen-heterocyclic Complexes Bind to DNA BT - Proceedings of the 4th International Conference on Mechatronics, Materials, Chemistry and Computer Engineering 2015 PB - Atlantis Press SP - 1127 EP - 1131 SN - 2352-538X UR - https://doi.org/10.2991/icmmcce-15.2015.192 DO - 10.2991/icmmcce-15.2015.192 ID - Zhao2015/12 ER -