Immunological aspects of the use of L-carnitine in sports nutrition

DOI

10.2991/icistis-19.2019.73How to use a DOI?

Keywords

sports nutrition, junior athletes, L-carnitine, immunity.

Abstract

The purpose of the work is to study the immunomodulating activity of L-carnitine in junior athletes during the training period. Materials and methods. 20 junior athletes (masters of sports and candidates for masters of sports in swimming) aged 14-18 years participated in the study. Athletes were divided into 2 groups of 10 people each. Athletes of the main group received L-carnitine (600 mg per day) for 4 weeks in addition to the basic diet. Athletes of the control group received only basic diet without sports nutrition. Examination of athletes was performed at the beginning and after 4 weeks of the observation period. Results. As a result of a comprehensive survey of junior athletes, the positive effect of L-carnitine intake on erythrocyte hemoglobin content (30.2 ± 0.4 pg vs 28.3 ± 0.3 pg at the beginning) was observed. The relative content of basophilic leukocytes in athletes of the main group statistically significantly decreased by the end of the observation period - from 0.64 ± 0.05% to 0.45 ± 0.04%, which indicated an increase in the body's resistance to allergic reactions. The biomarkers of the immunotropic effect of L-carnitine are a decrease in the expression of the apoptotic marker CD95/Fas on peripheral blood lymphocytes and suppression of the production of pro-inflammatory cytokines synthesized by Th1 lymphocytes with switching the response to humoral immunity. An evidence base for the effectiveness of the use of L-carnitine in sports nutrition for restoring immune dysfunction and adaptive potential of junior athletes has been provided.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Eleonora Trushina
AU  - Oksana Mustafina
AU  - Nikolay Riger
PY  - 2019/11
DA  - 2019/11
TI  - Immunological aspects of the use of L-carnitine in sports nutrition
BT  - Proceedings of the 4th International Conference on Innovations in Sports, Tourism and Instructional Science (ICISTIS 2019)
PB  - Atlantis Press
SP  - 288
EP  - 290
SN  - 2468-5739
UR  - https://doi.org/10.2991/icistis-19.2019.73
DO  - 10.2991/icistis-19.2019.73
ID  - Trushina2019/11
ER  -