Proceedings of the 5th International Conference on Information Engineering for Mechanics and Materials

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The synthesis of atorvastatin intermediates

Authors
Yuanjun Huang, Ting Liu
Corresponding Author
Yuanjun Huang
Available Online July 2015.
DOI
10.2991/icimm-15.2015.301How to use a DOI?
Keywords
atorvastatin; synthesis
Abstract

Adjust the dose of related synthetic method through the experiment, in order to improve the efficiency of the synthesis of intermediates. When adding catalyst 1.8 g, the product yield up to 63.11%; Adding 30g anhydrous ethanol yield up to 61.45%. different materials for the amount of drug income atorvastatin calcium middle size is different, the preparation should be select best dose.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 5th International Conference on Information Engineering for Mechanics and Materials
Series
Advances in Engineering Research
Publication Date
July 2015
ISBN
978-94-62520-88-2
ISSN
2352-5401
DOI
10.2991/icimm-15.2015.301How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Yuanjun Huang
AU  - Ting Liu
PY  - 2015/07
DA  - 2015/07
TI  - The synthesis of atorvastatin intermediates
BT  - Proceedings of the 5th International Conference on Information Engineering for Mechanics and Materials
PB  - Atlantis Press
SP  - 1627
EP  - 1629
SN  - 2352-5401
UR  - https://doi.org/10.2991/icimm-15.2015.301
DO  - 10.2991/icimm-15.2015.301
ID  - Huang2015/07
ER  -