The Role of Herbal Medicine in Suppressing the Incidence of Typhoid Fever in Indonesia

DOI

10.2991/978-94-6463-112-8_20How to use a DOI?

Keywords

manila fruit; typhoid fever; TNF-α

Abstract

Typhoid fever is one of the common diseases in developing countries. This is attributable to Salmonella typhi bacteria. The water from the unripe Manila sapodilla was often to be given as a drink on typhoid fever patients. Indonesia is a country that is rich in natural ingredients that can be used as medicine. Currently we are still faced with the problem of typhoid fever that never goes away in Indonesia. Many people in some areas have turned to herbal treatment using available natural ingredients to treat typhoid fever, one of which is to consume sapodilla manila fruit which is strong and effective enough to cure typhoid fever quickly. The method used in this study was to extract the manila sapodilla fruit with the maceration method which was then tested in vitro and in vivo to determine the effectiveness of the manila sapodilla fruit in reducing salmonella typhi colonies that cause typhoid fever. This study was an murine-based in vivo approach where our mice were divided into four groups: two treatment groups, and negative and positive references. Manila sapodilla fruit extract was used to reduce Salmonella typhi colonies that cause typhoid fever. Our results showed that there was a significant decrease in Salmonella typhi bacteria that was treated with Manila sapodilla extract at either dose of 510 mg and 750 mg. This suggested that sapodilla manila extract play a role in weakening Salmonella typhi colonies. Hence, this was deemed as a potential anti typhoid fever as a substitute for the use of antibiotics.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Hasta H. Idrus
AU  - Sunarno Sunarno
AU  - Ratih Rinendyaputri
AU  - Syamsu Rijal
AU  - Yusriani Mangarengi
AU  - Masriadi Masriadi
AU  - Rasfayanah Rasfayanah
AU  - Hermiaty Nasruddin
PY  - 2023
DA  - 2023/03/01
TI  - The Role of Herbal Medicine in Suppressing the Incidence of Typhoid Fever in Indonesia
BT  - Proceedings of the 1st International Conference for Health Research – BRIN (ICHR 2022)
PB  - Atlantis Press
SP  - 200
EP  - 209
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-112-8_20
DO  - 10.2991/978-94-6463-112-8_20
ID  - Idrus2023
ER  -