Differences in Estradiol Hormone Levels Based on the First Pregnant Age in Breast Cancer Women and Non Breast Cancer

DOI

10.2991/ahsr.k.220303.020How to use a DOI?

Keywords

Estradiol; Breast Cancer; First Pregnant Age

Abstract

The incidence of breast cancer in Indonesia reached 58,256 and was ranked first in 2018. Estrogen has an important role in breast cancer carcinogenesis, especially through the interaction of 17β-Estradiol. The purpose of this study was to determine the difference in average hormone levels based on the age of pregnant women with their first child after postmenopausal women with breast cancer and not breast cancer in Padang. This study was conducted on 36 postmenopausal women with breast cancer and 36 postmenopausal women without breast cancer at RST Reksodiwiryo TK III and RSK Bedah Ropanasuri from April to June 2019. Examination of estradiol hormone levels was carried out at the Biomedical Laboratory of Andalas University, Data were analyzed by T-test independent. The results showed that there was no significant difference between the mean estradiol hormone levels of pregnant women with their first child aged 30 years and <30 years of age in postmenopausal women with breast cancer (84.54 vs 45.10 pg/ml, p> 0.05) and not there is a significant difference between the mean levels of the hormone estradiol in pregnant women with their first child aged 30 years and <30 years in postmenopausal women without breast cancer (48.92 vs 49.18 pg/ml, p> 0.34). The conclusion of this study is that there is no difference in the average level of the hormone estradiol based on the age of pregnant women with their first child in postmenopausal women with breast cancer and not breast cancer in Padang.

Copyright

© 2022 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Nirmala Sari
AU  - Firdawati Firdawati
PY  - 2022
DA  - 2022/03/08
TI  - Differences in Estradiol Hormone Levels Based on the First Pregnant Age in Breast Cancer Women and Non Breast Cancer
BT  - Proceedings of 1st International Conference on Health Sciences and Biotechnology (ICHB 2021)
PB  - Atlantis Press
SP  - 102
EP  - 104
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220303.020
DO  - 10.2991/ahsr.k.220303.020
ID  - Sari2022
ER  -