Proceedings of the 12th International Conference on Green Technology (ICGT 2022)

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Gen AdipoQ Polymorphism on Type 2 Diabetes Mellitus Patients

Authors
Tyas Nyonita Punjungsari1, *
1Biologi Department, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang, Indonesia
*Corresponding author. Email: tyasnyonita@uin-malang.ac.id
Corresponding Author
Tyas Nyonita Punjungsari
Available Online 29 May 2023.
DOI
10.2991/978-94-6463-148-7_41How to use a DOI?
Keywords
ADIPOQ; SNPs; Type 2 Diabetes Mellitus; T2DM
Abstract

DNA polymorphisms is variation on DNA sequence that change amino acid and gene function through changes in splicing, one of this polymorphism was SNP which only one nucleotide that change on target sequence. A survey that comprised 44 single nucleotide polymorphism (SNP)s of 31 candidate genes related to the lipid metabolism such as SNP on Gene AdipoQ, which affect some metabolite disease such as type 2 diabetes mellitus (T2DM). To identified those we need identifying some patient T2DM gen for understanding this fenomenon. Method of this research is descriptive exploration using type 2 diabetes mellitus patients in Gledug Village, Blitar Regency as specimen donors. Identification using DNA extraction, DNA Amplification, sequencing and bioinformatics analysis. The results of this project seven DNA extracted, the seven sequences have the same Qv20 + value as the sequence base pair, alignment analysis using blast, when compared with the adipoQ gene sequence with accession number NG_021140.1, it was found that the KT, SR and BP sequences had a 100% similarity level. Identification of candidate SNPs in the absence of the adenine nucleotide was found in the SR, KT, and ST sequences.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 12th International Conference on Green Technology (ICGT 2022)
Series
Advances in Engineering Research
Publication Date
29 May 2023
ISBN
978-94-6463-148-7
ISSN
2352-5401
DOI
10.2991/978-94-6463-148-7_41How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Tyas Nyonita Punjungsari
PY  - 2023
DA  - 2023/05/29
TI  - Gen AdipoQ Polymorphism on Type 2 Diabetes Mellitus Patients
BT  - Proceedings of the 12th International Conference on Green Technology (ICGT 2022)
PB  - Atlantis Press
SP  - 416
EP  - 422
SN  - 2352-5401
UR  - https://doi.org/10.2991/978-94-6463-148-7_41
DO  - 10.2991/978-94-6463-148-7_41
ID  - Punjungsari2023
ER  -