Experimental Research and Analysis of Hedysari Total Polysaccharides in Vivo Mice Antineoplastic

DOI

10.2991/icesame-16.2016.87How to use a DOI?

Keywords

Hedysari total polysaccharides; Tumor; Antineoplastic; Experimental study

Abstract

Objective: To analyze the study Hedysari polysaccharide on anti-tumor effects in mice and study its mechanisms. Methods: Hedysari through water extraction and other methods to remove the protein extract Hedysari total polysaccharides, using high performance gel filtration chromatography method Hedysari total polysaccharides were determined. A total of 40 mice were chosen to study the 40 mice were divided into a control group, Hedysari total polysaccharide group, cyclic amide groups, cyclic amide joint Hedysari total polysaccharide groups of 10. Which group was given normal saline, the other groups of mice were given the drug correspond to observe tumor cases (tumor weight, thymus index, platelets, NK cells, CD3 + cells) four groups of mice. Results: Compared with the control group, the other three sets of thymus, spleen index and other significant changes, CD3 + T cells were reduced, NK cells reduced, compared to p <0.05, the difference was statistically significant. Comparison of the combined group and monotherapy groups of mice, the thymus index, spleen index, CD4 + T cells and white blood cells have significant changes, p <0.05, the difference was statistically significant. Conclusion: Hedysari total polysaccharides can have better tumor suppression effect, reducing immunosuppression, and enhance the body's anti-tumor ability.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Yongqing Wang
PY  - 2016/03
DA  - 2016/03
TI  - Experimental Research and Analysis of Hedysari Total Polysaccharides in Vivo Mice Antineoplastic
BT  - Proceedings of the 2016 International Conference on Education, Sports, Arts and Management Engineering
PB  - Atlantis Press
SP  - 412
EP  - 415
SN  - 2352-5398
UR  - https://doi.org/10.2991/icesame-16.2016.87
DO  - 10.2991/icesame-16.2016.87
ID  - Wang2016/03
ER  -