Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021)

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The Effects of Kefir and Jicama Synbiotic Administration on White Rat Serum Cortisol Levels After Subtotal Nephrectomy

Authors
Miranti Dewi Pramaningtyas1, *, Rokhima Lusiantari1, Titis Nurmasitoh1, Ernadita Budiastuti1, Qudsia Umaira Khan2, Rafik Prabowo1, Mohammad Alvian Subhakti1, Hana Afifah Firdaus1, Bagastyo Afif Prabowo1, Chairun Nisa’ Nur’aini1, Silvi Rahmawati1, Muhammad Hanif Al As’ad Budiyanto1, Clarinta Belva Sabina1, Salama Suci Nurani1, Alzena Zada Nur Safira1
1Department of Physiology, Faculty of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia
2Department of Physiology, CMH Lahore Medical and Dental College, Lahore, Punjab, Pakistan
*Corresponding author. Email: miranti.dewi@uii.ac.id
Corresponding Author
Miranti Dewi Pramaningtyas
Available Online 19 December 2022.
DOI
10.2991/978-94-6463-048-0_53How to use a DOI?
Keywords
Synbiotics; Kefir; Jicama; Cortisol; Subtotal nephrectomy
Abstract

Changes in the kidneys can lead to increased blood pressure, which can be followed by an increase in cortisol levels. Subtotal nephrectomy is one of the methods to provide animal models of hypertension. The combination of kefir milk and jicama as a synbiotic drink is expected to maintain cortisol under normal levels in hypertensive conditions. Aim: This study aims to determine the effect of kefir and jicama synbiotic beverage on rats’ serum cortisol levels after a subtotal nephrectomy procedure. Methods: Male Wistar rats were divided into five groups, i.e. a group of subtotal nephrectomy, sham group, and three synbiotic groups receiving subtotal nephrectomy procedure and synbiotics with differences in composition (Syn 1, Syn 2, and Syn 3). The serum cortisol levels were measured with ELISA after a month of kefir and jicama synbiotic administration. The results were analyzed statistically using one-way ANOVA. Results: The serum cortisol levels (ng/mL) were 165.49 ± 33.73, 150.90 ± 51.54, 158.77 ± 27.17, 119.64 ± 79.20, and 168.06 ± 19.19 respectively for subtotal nephrectomy, sham group, Syn 1, Syn 2, and Syn 3 groups. The one-way ANOVA statistical analysis obtained a p = 0.386, which showed no significant differences between groups. The administration of kefir and jicama as a synbiotic beverage has no significant effects on rat's serum cortisol levels after subtotal nephrectomy.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021)
Series
Advances in Health Sciences Research
Publication Date
19 December 2022
ISBN
978-94-6463-048-0
ISSN
2468-5739
DOI
10.2991/978-94-6463-048-0_53How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Miranti Dewi Pramaningtyas
AU  - Rokhima Lusiantari
AU  - Titis Nurmasitoh
AU  - Ernadita Budiastuti
AU  - Qudsia Umaira Khan
AU  - Rafik Prabowo
AU  - Mohammad Alvian Subhakti
AU  - Hana Afifah Firdaus
AU  - Bagastyo Afif Prabowo
AU  - Chairun Nisa’ Nur’aini
AU  - Silvi Rahmawati
AU  - Muhammad Hanif Al As’ad Budiyanto
AU  - Clarinta Belva Sabina
AU  - Salama Suci Nurani
AU  - Alzena Zada Nur Safira
PY  - 2022
DA  - 2022/12/19
TI  - The Effects of Kefir and Jicama Synbiotic Administration on White Rat Serum Cortisol Levels After Subtotal Nephrectomy
BT  - Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021)
PB  - Atlantis Press
SP  - 462
EP  - 466
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-048-0_53
DO  - 10.2991/978-94-6463-048-0_53
ID  - Pramaningtyas2022
ER  -