The Potency of Red Betel (Piper crocatum Ruiz & Pav.) Methanolic Extract as α-Amylase and α-Glucosidase Inhibitor

DOI

10.2991/absr.k.220406.031How to use a DOI?

Keywords

α-amylase; α-glucosidase; Methanolic extract; Piper crocatum

Abstract

Methanol is an effective menstruum for attracting compounds with various pharmacological activities from Piper crocatum Ruiz & Pav. Several studies reported that laboratory tests for reducing blood sugar content of red betel extract such as aqueous, ethanolic, and ethyl acetate extracts. This study aimed to investigate the actions of red betel leaves methanolic extract in reducing α-amylase and α-glucosidase in an in-vitro study. The test for decreasing the actions of the enzymes was done using the ultraviolet-visible spectrophotometric method. The test was run by observing carbohydrates left by knowing the effect of iodine-iodide resulting in a blue complex. The red betel leaves extract demonstrated an adequate α-amylase and α-glucosidase inhibitory activity as shown by the IC₅₀ of 8.463 ± 0.318 mg/mL and 10.013 ± 0.070 mg/mL, respectively.

Copyright

© 2022 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license.

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TY  - CONF
AU  - Yustina Sri Hartini
AU  - Dewi Setyaningsih
PY  - 2022
DA  - 2022/05/02
TI  - The Potency of Red Betel (Piper crocatum Ruiz & Pav.) Methanolic Extract as α-Amylase and α-Glucosidase Inhibitor
BT  - Proceedings of the 7th International Conference on Biological Science (ICBS 2021)
PB  - Atlantis Press
SP  - 209
EP  - 212
SN  - 2468-5747
UR  - https://doi.org/10.2991/absr.k.220406.031
DO  - 10.2991/absr.k.220406.031
ID  - Hartini2022
ER  -