Plasma Exchange Plus Mycophenolate Mofetil, Hormones with Severe Systemic Lupus Erythematosus Serum Autoantibodies

DOI

10.2991/icamcs-16.2016.3How to use a DOI?

Keywords

Plasmapheresis, mycophenolate mofetil, hormone, severe systemic lupus erythematosus, serum autoantibodies

Abstract

Analysis and Discussion plasmapheresis combined hormone, influence of mycophenolate mofetil on children with severe systemic lupus erythematosus autoantibodies. 80 cases in April 2013-Children with systemic lupus erythematosus in April 2015 in our hospital for treatment,in a random manner which were divided into two groups,namely: the control group and the observation group,the control group of patients children simple line of MMF combined hormone therapy in the treatment group,based on the observation of the patient group were treated with plasma exchange treatment,compared two groups of children with changes in the indicators and efficacy. The two groups of children after treatment,all patients anti-ds-DNA,SM antibody detection rate was significantly lower than before treatment,P<0.05, group of children was lower than that observed in children in the control group,P<0.05,anti-RNP antibody detection rate did not change significantly,P>0.05.Compared with the previous treatment,were significantly increased in children with Cre children control group after treatment in the observation group,24h urine protein and ESR and other indicators,and the children of C3 decreased,compared with the control group,patients in the observation group the indicators improved obviously,P<0.05. Patients observation group was 97.5%,the effective treatment of patients in the control group was 82.5% in the observation group patients was significantly higher efficiency,P<0.05, statistically significant.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Ping Shuai
AU  - Dan Guo
PY  - 2016/06
DA  - 2016/06
TI  - Plasma Exchange Plus Mycophenolate Mofetil, Hormones with Severe Systemic Lupus Erythematosus Serum Autoantibodies
BT  - Proceedings of the 2016 5th International Conference on Advanced Materials and Computer Science
PB  - Atlantis Press
SP  - 10
EP  - 13
SN  - 2352-5401
UR  - https://doi.org/10.2991/icamcs-16.2016.3
DO  - 10.2991/icamcs-16.2016.3
ID  - Shuai2016/06
ER  -