A Potential Anti-schistosomal Agent Containing 1,2,5-Oxadiazole-2-oxide and Praziquante Moieties

DOI

10.2991/ic3me-15.2015.25How to use a DOI?

Keywords

Sulfone; 1,2,5-Oxadiazole; Praziquante; Anti-schistosomal Agent

Abstract

3-Praziquantel-4-(4-chlorophenylsulfonyl)-1,2,5-oxadiazol-2-oxide was synthesized via the coupling reaction of praziquante and 1,2,5-oxadiazole in ethylene glycol, and its molecular structure was confirmed by the melting point and spectroscopic data (UV, IR, and 1H NMR). Moreover, it may be a potential anti-schistosmal agent.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Qinghao Wang
AU  - Xionglu Zhang
PY  - 2015/08
DA  - 2015/08
TI  - A Potential Anti-schistosomal Agent Containing 1,2,5-Oxadiazole-2-oxide and Praziquante Moieties
BT  - Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
PB  - Atlantis Press
SP  - 133
EP  - 136
SN  - 2352-5401
UR  - https://doi.org/10.2991/ic3me-15.2015.25
DO  - 10.2991/ic3me-15.2015.25
ID  - Wang2015/08
ER  -