Influence of Intermittent Fasting to Body Weight and Blood Glucose Levels in White Rats with Diabetes Mellitus Model

DOI

10.2991/978-2-38476-110-4_41How to use a DOI?

Keywords

Diabetes mellitus; intermittent fasting diet; weight; blood glucose level

Abstract

Diabetes mellitus is a metabolic disorder in the form of hyperglycemia caused by many factors. An intermittent fasting diet is a diet modification that can cause a decrease in adiposity which affects the increase in leptin and adiponectin sensitivity. This study aimed to determine the effect of average blood glucose levels in white rats with Diabetes Mellitus Model with intermittent fasting diet intervention compared to controls. The method is an experimental laboratory-only post-test group design. The research was conducted at the Animal House, Faculty of Medicine and Health Sciences, Jambi University, and the Jambi Provincial Health Laboratory. White rats (Rattus norvegicus) Wistar strain with diabetes mellitus model 2–3 months old and no anatomical abnormalities were divided into two groups: control (n = 10) which received an ad libitum diet, and intermittent fasting (n = 10) diet. Blood glucose levels were measured before and after treatment. Results Intermittent fasting diet can reduce weight in white rats with diabetes mellitus model (mean = 196.4) compared to the control group (mean 243.52), reduce blood glucose levels in white rats with diabetes mellitus model (mean pretest = 133.53, mean post-test = 113.47) compared to control (mean pretest = 103.68, mean post-test = 121.46) (Mann -Whitney test; p < 0.05). The conclusion is that intermittent fasting can reduce weight and blood glucose levels in white rats with diabetes mellitus model.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Huntari Harahap
AU  - Erny Kusdiyah
AU  - Esa Indah Ayudia
PY  - 2023
DA  - 2023/11/07
TI  - Influence of Intermittent Fasting to Body Weight and Blood Glucose Levels in White Rats with Diabetes Mellitus Model
BT  - Proceedings of the 4th Green Development International Conference (GDIC 2022)
PB  - Atlantis Press
SP  - 388
EP  - 392
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-110-4_41
DO  - 10.2991/978-2-38476-110-4_41
ID  - Harahap2023
ER  -