Proceedings of the 6th International Conference on Electronic, Mechanical, Information and Management Society

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The Lipase-catalyzed Synthesis of Ethyl Ferulate

Authors
Qiannan Wang, Wei Zhang, Jiaying Xin
Corresponding Author
Qiannan Wang
Available Online April 2016.
DOI
10.2991/emim-16.2016.351How to use a DOI?
Keywords
Lipase; Ethyl ferulate; Biocatalytic synthesis; Ferulic acid
Abstract

Selective biocatalytic synthesis is an important part of the third generation of biotechnology, is the forefront of international scientific and technological development. Utilizing enzyme catalyzed reaction, many complex substances can be synthesized. Biocatalysis have strict regional selectivity and enantioselectivity. Ferulic acid is naturally safe radical quencher and anti-oxidation agent. In the cosmetics industry, ferulic acid is considered to be the best natural sunscreen, also used as skin whitening agents. Ferulic acid and its derivatives are widely used in the pharmaceutical industry, the application in the food industry are also increasing. This paper studied the immobilized lipase-catalyzed synthesis of ethyl ferulate in organic medium. Lipase from Mucor sp.M-2 was immobilized with diatomite powder as the carrier by absorption and was used as biocatalyst. The reaction medium were compared for biocatalytic synthesis of ethyl ferulate. The optimum solvent is tert-butyl alcohol .The opitimization of reaction conditions was obtained. In the 4ml of tert butyl alcohol, when the molar ratio of acid to alcohol is 1.5:1 ,the temperature is 45 degrees centigrade, a yield of 9.9% for ethyl ferulate can be obtained after 120h.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 6th International Conference on Electronic, Mechanical, Information and Management Society
Series
Advances in Computer Science Research
Publication Date
April 2016
ISBN
978-94-6252-176-6
ISSN
2352-538X
DOI
10.2991/emim-16.2016.351How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Qiannan Wang
AU  - Wei Zhang
AU  - Jiaying Xin
PY  - 2016/04
DA  - 2016/04
TI  - The Lipase-catalyzed Synthesis of Ethyl Ferulate
BT  - Proceedings of the 6th International Conference on Electronic, Mechanical, Information and Management Society
PB  - Atlantis Press
SP  - 1728
EP  - 1732
SN  - 2352-538X
UR  - https://doi.org/10.2991/emim-16.2016.351
DO  - 10.2991/emim-16.2016.351
ID  - Wang2016/04
ER  -