The Novel Paradigm of Stroke Mechanism Research and Development Based on Neurovascular Unit

DOI

10.2991/emim-15.2015.55How to use a DOI?

Keywords

Neurovascular unit; Stroke; neurons; Blood-brain barrier (BBB);

Abstract

Objective: Stroke is a kind of disease with high morbidity, high mortality and high disability rate. Since currently available drugs treating cerebral ischemia have many limitations, it is necessary to find a new treatment approaches. The emergence of neurovascular unit provides a new perspective for basic research of stroke. Methods: Summarize the literature of research data relevant on the neurovascular unit and ischemia stroke, looking for the new treatment targets in the neurovascular unit during stroke process. Results: Checking out dozens of foreign literature, it shows that neurovascular unit plays an important role during the pathological and healing process of stroke. Conclusion: Neurovascular unit associated with the concept of the stroke into an integrated tissue reaction among all the cells and matrix components involved in the process of tissue damage, not just neurons or blood vessels involved in the pathological reactions. The concept will brought new opportunities for the treatment of stroke.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Qingshan Liu
AU  - Weiwei Zhang
AU  - Xu Li
AU  - Xiaoying Yin
PY  - 2015/04
DA  - 2015/04
TI  - The Novel Paradigm of Stroke Mechanism Research and Development Based on Neurovascular Unit
BT  - Proceedings of the 2015 International Conference on Education, Management, Information and Medicine
PB  - Atlantis Press
SP  - 284
EP  - 287
SN  - 2352-5428
UR  - https://doi.org/10.2991/emim-15.2015.55
DO  - 10.2991/emim-15.2015.55
ID  - Liu2015/04
ER  -