Synthesis and Characterization of Molecularly Imprinted Polymer Caffeine Using Acrylamide as Monomer

DOI

10.2991/ahsr.k.200523.028How to use a DOI?

Keywords

MIP, caffeine, acrylamide, FTIR, MISPE

Abstract

Objectives: Molecularly Imprinted Polymer (MIP) is a selective polymer that can bind target molecules, is made with a ratio 1:4:20 (mmol) between caffeine, acrylamide, and ethylene glycol dimethacrylate. The ratio will form a polymer that will be released again so that it can selectively recapture the template. Method: The synthesis method of MIP and NIP was using the bulk method with direct heating at 60oC for 8 hours. Molecular release using extraction and sonication method with chloroform solvent resulted in 20 times the recovery until the value released below the selection limit of 1.173 ppm. To find out the effectiveness of polymers in capturing the template, a batch method was repeated on theophylline with were the same xanthine derivates. Results and Discussion: Polymers against caffeine are more selective than theophylline which is 76.55% and theophylline is only 1.31%. Fourier Transform Infra-Red (FTIR) was using characterization, there is a functional group of differences between the FTIR spectrum of caffeine, MIP with caffeine, MIP without caffeine and NIP. Conclusion: The resulting adsorb of MIP has a selective than NIP with value Imprinting Factor (IF) 1.26. Of the sample testing obtained MISPE has a selective than NISPE with the percentage of concentration analgesic drug sample 82.01% and energy drink sample 84.01%.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Saeful Amin
AU  - Shelma Az Zahra
AU  - Dang Soni
PY  - 2020
DA  - 2020/06/08
TI  - Synthesis and Characterization of Molecularly Imprinted Polymer Caffeine Using Acrylamide as Monomer
BT  - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019)
PB  - Atlantis Press
SP  - 114
EP  - 117
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.200523.028
DO  - 10.2991/ahsr.k.200523.028
ID  - Amin2020
ER  -