Inhibitory Activity of Tyrosinase Enzyme on Lotion Contains Pear (Pyrus pyrifolia (Burm.F) Nakai) Rind Extract

DOI

10.2991/ahsr.k.200523.022How to use a DOI?

Keywords

pears (Pyrus pyrifolia (Burm.f.) Nakai), skin lightening, lotion, tyrosinase enzyme

Abstract

Objectives: The purpose of this study was to make lotion preparations containing ethanol extract of pear rind and to test the inhibitory activity of the tyrosinase enzyme from pear rind ethanol extract lotion preparations. Method: Determination of tyrosinase enzyme inhibitory activity was carried out using a microplate reader instrument. The formula used is ethanol extract of pear rind, stearic acid, cetyl alcohol, triethanolamine, liquid paraffin, glycerin, sodium benzoate, essense pear and distilled water. Results and Discussion: Ethanol extract of pear rind has tyrosinase enzyme inhibiting activity which is indicated by IC50 values of 520.45 μg/mL, and in lotion preparations it has tyrosinase enzyme inhibitory activity which is indicated by IC50 values of 599.96 μg/mL. Conclusion: From the results of tyrosinase inhibitory activity test, lotion containing ethanol extract of pear rind has the potential to be a skin lightening.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Deby Tristiyanti
AU  - Ledianasari
AU  - Silva Oktaviani
PY  - 2020
DA  - 2020/06/08
TI  - Inhibitory Activity of Tyrosinase Enzyme on Lotion Contains Pear (Pyrus pyrifolia (Burm.F) Nakai) Rind Extract
BT  - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019)
PB  - Atlantis Press
SP  - 88
EP  - 91
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.200523.022
DO  - 10.2991/ahsr.k.200523.022
ID  - Tristiyanti2020
ER  -