Antifertility Effect of N-hexane, Ethyl Acetate and Water Fractions from Carica papaya Leaves on Sperm Motility in Male Wistar Rats

DOI

10.2991/ahsr.k.200523.038How to use a DOI?

Keywords

antifertility, Carica papaya, sperm motility, N-hexane, ethyl acetate, water fraction

Abstract

Objective: The aim of this study was to investigate the antifertility effect of N-hexane, ethyl acetate, and water fractions from C. papaya leaves on sperm motility in male Wistar rats. Method: Twenty four rats used in this study. Rats were devided into 4 groups: normal group and Carica papaya fraction group (N-hexane; ethyl acetate; and water). Rats were given Carica papaya fractions at dose 0.4 g/ Kg BW rat/day for 20 days). Carica papaya leaves were extracted by ethanol and did fractionation by liquid-liquid methods. Results and Discussion: The results of this study were N-hexane, ethyl acetate and water fractions significantly (P<0.05) produced decreased in sperm motility compered with normal group. The decresed Carica papaya fractions (N-hexane, ethyl acetate and water) were 33 %, 65%, and 75% respectively. Conclusion: Carica papaya fractions (N-hexane, ethyl acetate and water) have antifertility effect on sperm motility.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Nur Laili Dwi Hidayati
PY  - 2020
DA  - 2020/06/08
TI  - Antifertility Effect of N-hexane, Ethyl Acetate and Water Fractions from Carica papaya Leaves on Sperm Motility in Male Wistar Rats
BT  - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019)
PB  - Atlantis Press
SP  - 155
EP  - 158
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.200523.038
DO  - 10.2991/ahsr.k.200523.038
ID  - Hidayati2020
ER  -