Degradation, Characterization, Ferrous Ion Chelating Ability and Repair Effect of Sulfated Polysaccharides of Six Kinds of Seaweed Polysaccharides

DOI

10.2991/bst-17.2018.32How to use a DOI?

Keywords

Antioxidant, Cell repair, Sulfated polysaccharides

Abstract

Six kinds of seaweed polysaccharides (SPSs) extracted from Laminaria japonica, Porphyra yezoensis, Gracilaria lemaneiformis, Sargassum fusiforme, Eucheuma gelatinae and Undaria pinnatifida were degraded and characterized. The sulfate group (-OSO3H) content of these polysaccharides were 21.7, 17.9, 13.3, 8.2, 7.0, and 5.5%, respectively. The ferrous ion chelating ability and repair effect on injured human kidney proximal tubular epithelial cells (HK-2) of these polysaccharides were studied. These polysaccharides had stronger ferrous ion chelating ability, suggesting that it possessed high antioxidant activity. Each polysaccharide had a repair effect on oxalate-induced damaged HK-2 cells. The antioxidant activity and repair ability of polysaccharide was positively correlated with its -OSO3H content. These results indicated that these polysaccharides, especially those with high -OSO3H content, may be potential drugs for the prevention and treatment of calcium oxalate stones.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Xin-Yuan Sun
AU  - Da Guo
AU  - Jian-Min Wang
AU  - Jian-Ming Ouyang
PY  - 2018/02
DA  - 2018/02
TI  - Degradation, Characterization, Ferrous Ion Chelating Ability and Repair Effect of Sulfated Polysaccharides of Six Kinds of Seaweed Polysaccharides
BT  - Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
PB  - Atlantis Press
SP  - 220
EP  - 226
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-17.2018.32
DO  - 10.2991/bst-17.2018.32
ID  - Sun2018/02
ER  -