Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)

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The Identification of Default Mode Network in Rhesus Macaque Using Resting-State fMRI

Authors
Xiao-Wei Fu, Cheng-Zhen Guo, Peng-Cheng Li, Dan-Zhou Yang, Ying Zhang
Corresponding Author
Xiao-Wei Fu
Available Online February 2018.
DOI
10.2991/bst-17.2018.13How to use a DOI?
Keywords
fMRI, Resting-State, Rhesus macaques, Default mode network, Independent component analysis.
Abstract

To investigate Default Mode Network (DMN) in healthy rhesus monkey brain using Resting-State functional Magnetic Resonance Imaging (RS-fMRI). Under anesthesia, two healthy rhesus macaques underwent RS-fMRI at 7.0T using equal imaging parameters. The functional images were first spatially normalized to the standard rhesus monkey template 112SM-RL-T1, and the GIFT software was utilized to carry out group-level Independent Component Analysis (group-ICA) on all preprocessed functional images. The results demonstrated that our method can obtain functional connectivity maps of the resting-state networks. Among them, the DMN bilaterally includes posterior cingulate cortex, anterior cingulate cortex, medial parietal cortex, retrosplenial cortex, arcuate sulcus, ventral intraparietal area, temporo-parietal area, superior temporal sulcus dorsal bank and a portion of visual cortex. With the help of cutting-edge 7.0T fMRI technology, our result confirms that the DMN of the monkey brain highly resembles the ones in human; it supports the notion that non-primates are useful models for neuropharmacological and neurocognitive studies.

Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
Series
Advances in Biological Sciences Research
Publication Date
February 2018
ISBN
978-94-6252-472-9
ISSN
2468-5747
DOI
10.2991/bst-17.2018.13How to use a DOI?
Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Xiao-Wei Fu
AU  - Cheng-Zhen Guo
AU  - Peng-Cheng Li
AU  - Dan-Zhou Yang
AU  - Ying Zhang
PY  - 2018/02
DA  - 2018/02
TI  - The Identification of Default Mode Network in Rhesus Macaque Using Resting-State fMRI
BT  - Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
PB  - Atlantis Press
SP  - 80
EP  - 86
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-17.2018.13
DO  - 10.2991/bst-17.2018.13
ID  - Fu2018/02
ER  -