The Role of Fusobacterium Nucleatum on Chronic Periodontitis (Literature Review)

DOI

10.2991/ahsr.k.210201.004How to use a DOI?

Keywords

Fusobacterium nucleatum, chronic periodontitis, lipopolysaccharides

Abstract

Chronic periodontitis is the most often disease in the oral cavity which attacks the supporting tissues of the teeth. This disease develops slowly, resulting in teeth experiencing loss of attachment and alveolar bone loss. The main cause of chronic periodontitis is bacterial plaque which is a soft deposit in the form of a thin layer of biofilm containing a collection of pathogenic microorganisms, one of it is Fusobacterium nucleatum. Fusobacterium nucleatum is an obligate anaerobic Gram negative bacterium and found in a healthy or diseased oral cavity. Fusobacterium nucleatum can be isolated from the oral cavity and other infections in the human body such as skin ulcers, peritonsillar abscesses, septic arthritis and endocarditis. Fusobacterium nucleatum plays an important role in the formation of plaque because it functions as a "bridge bacterium", which is a link for bacteria found in the early phases of plaque colonization with bacteria found in the final plaque colonization. Fusobacterium nucleatum is one of the bacteria most isolated from periodontal pocket of patients with chronic periodontitis. Lipopolysaccharides found on the outer membrane of Fusobacterium nucleatum and metabolic result from this bacteria can cause periodontal tissue damage in the cases of chronic periodontitis.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Dewi Saputri
AU  - Mahdi Abrar
AU  - Zaki Mubarak
AU  - Mudatsir
PY  - 2021
DA  - 2021/02/01
TI  - The Role of Fusobacterium Nucleatum on Chronic Periodontitis (Literature Review)
BT  - Proceedings of the 1st Aceh International Dental Meeting (AIDEM 2019), Oral Health International Conference On Art, Nature And Material Science Development 2019
PB  - Atlantis Press
SP  - 17
EP  - 21
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210201.004
DO  - 10.2991/ahsr.k.210201.004
ID  - Saputri2021
ER  -