Anti-Fatigue and Anti-Hypoxic Effects of Lycium barbarum Polysaccharides

DOI

10.2991/aeece-15.2015.137How to use a DOI?

Keywords

Lycium barbarum polysaccharides; forced swimming test; normobaric hypoxia test; anti-fatigue; anti-hypoxic

Abstract

The purpose of the present study was to evaluate the anti-fatigue and anti-hypoxic effects of Lycium barbarum polysaccharides (LBP) in mice. The mice were randomly divided into four groups, a control group and three treatment groups. The treated groups received different doses of LBP (125, 250 and 500 mg/kg body) by gavage every day for 28 days, while the control group received distilled water. Forced swimming test and normobaric hypoxia test were conducted on the final day of experimentation. The results showed that LBP could extend the exhaustive swimming time, decrease the blood lactic acid (BLA) and serum urea nitrogen (SUN) levels, and increase liver and muscle glycogen contents in forced swimming test. Meanwhile, LBP could extend hypoxic survival time in normobaric hypoxia test. This indicated that LBP had anti-fatigue and anti-hypoxic effects.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Ming Wu
AU  - Liquan Guo
PY  - 2015/09
DA  - 2015/09
TI  - Anti-Fatigue and Anti-Hypoxic Effects of Lycium barbarum Polysaccharides
BT  - Proceedings of the International Conference on Advances in Energy, Environment and Chemical Engineering
PB  - Atlantis Press
SP  - 686
EP  - 689
SN  - 2352-5401
UR  - https://doi.org/10.2991/aeece-15.2015.137
DO  - 10.2991/aeece-15.2015.137
ID  - Wu2015/09
ER  -