Determinants of Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia

DOI

10.2991/acpes-19.2019.68How to use a DOI?

Keywords

Determinant, drug-resistant, tuberculosis

Abstract

Indonesia ranked 6th from countries with the highest burden of drug-resistant pulmonary tuberculosis (PTB). A rate of 1.9% of new cases develop to be resistant and even 12% from previous treated cases. Previous studies concluded determinants of drug-resistant PTB, however, the study in Indonesia, especially in the scope of hospitals is still limited. Our study aims to explore the determinant of drug-resistant PTB in Dr. Kariadi General Hospital. We conducted a case-control study, using data from medical records. A sample of 76 cases and 76 controls have met the criterion and were involved in the study. The status of drug-resistant cases determined by rapid molecular test. We observed the subject’s characteristics and determinants of drug-resistant PTB. Study shows that there is no significant difference in the subject’s characteristics, i.e. age, sex, level of education, and working status between the group of cases and controls. Chi-square analysis shows that history of previous treatment, HIV infection, drug side-effects status, Acid-Fast Bacilli (AFB) gradation, and duration of treatment were related to drug-resistant pulmonary TB. After conducted Binary Logistic Regression, we concluded that history of treatment (OR=24.3; 95%CI: 8.49-69.33) and AFB gradation (OR=13.8; 95% CI: 2.76-68.60) altogether as dominant determinants of drug-resistant PTB.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Mahalul Azam
AU  - Ucu Yulia
AU  - Muhamad Zakki Saefurrohim
AU  - Arulita Ika Fibriana
PY  - 2019/11
DA  - 2019/11
TI  - Determinants of  Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia
BT  - Proceedings of the 5th International Conference on Physical Education, Sport, and Health (ACPES 2019)
PB  - Atlantis Press
SP  - 301
EP  - 304
SN  - 2352-5398
UR  - https://doi.org/10.2991/acpes-19.2019.68
DO  - 10.2991/acpes-19.2019.68
ID  - Azam2019/11
ER  -