Journal of Epidemiology and Global Health

Volume 4, Issue 3, September 2014, Pages 245 - 247

Objective cardiac markers and cerebrovascular lesions in Indian seniors

Authors
Stephanie H. Charles1, Stephanie.charles@med.einstein.yu.edu, Amanda C. Tow1, Amanda.tow@med.einstein.yu.edu, Joe Verghese*, Joe.verghese@einstein.yu.edu
Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Room 301, Bronx, NY 10461, USA
Department of Medicine, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Room 301, Bronx, NY 10461, USA
1

contributed equally as first authors.

*Corresponding author. Address: Division of Cognitive & Motor Aging, Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Room 301, Bronx, NY 10461, USA. Tel.: +1 718 430 3808; fax: +1 718 430 3829.
Corresponding Author
Received 28 August 2013, Revised 25 December 2013, Accepted 22 February 2014, Available Online 29 March 2014.
DOI
10.1016/j.jegh.2014.02.003How to use a DOI?
Keywords
Dementia; EKG; Echocardiogram; MRI; Cerebrovascular disease
Abstract

Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p < .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas.

Copyright
© 2014 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Journal
Journal of Epidemiology and Global Health
Volume-Issue
4 - 3
Pages
245 - 247
Publication Date
2014/03/29
ISSN (Online)
2210-6014
ISSN (Print)
2210-6006
DOI
10.1016/j.jegh.2014.02.003How to use a DOI?
Copyright
© 2014 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Cite this article

TY  - JOUR
AU  - Stephanie H. Charles
AU  - Amanda C. Tow
AU  - Joe Verghese
PY  - 2014
DA  - 2014/03/29
TI  - Objective cardiac markers and cerebrovascular lesions in Indian seniors
JO  - Journal of Epidemiology and Global Health
SP  - 245
EP  - 247
VL  - 4
IS  - 3
SN  - 2210-6014
UR  - https://doi.org/10.1016/j.jegh.2014.02.003
DO  - 10.1016/j.jegh.2014.02.003
ID  - Charles2014
ER  -