Artery Research

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Volume 7, Issue 3-4, September 2013, Pages 135 - 135

P3.31 CORRELATION OF CENTRAL HAEMODYNAMICS WITH HEALTH-RELATED QUALITY OF LIFE

Authors
D.A. Vrachatis1, 2, 3, A. Argyris1, A. Papadopoulos2, T.G. Papaioannou3, E. Aissopou1, G. Konstantonis1, D. Niakas2, P. Sfikakis1, A. Protogerou1
1Cardiovascular Research Laboratory, First Dpt. of Propedeutic Medicine, National & Kapodistrian University of Athens, Athens, Greece
2Faculty of Social Sciences, Hellenic Open University, Patras, Greece
3First Dpt. of Cardiology, National & Kapodistrian University of Athens, Athens, Greece
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.118How to use a DOI?
Abstract

Objectives: High blood pressure (BP) levels have been reported to have an inverse association with the health-related quality of life (HRQOL). Moreover, the value of central beyond peripheral haemodynamics has been illustrated by a series of studies. We sought to investigate potential correlations between central haemodynamics and HRQOL.

Methods: Brachial BP was evaluated with an automatic, oscillometric device (WatchBP, Microlife). Central haemodynamics (aortic BP, augmentation index (AIx), augmentation pressure (AP)) were assessed using applanation tonometry (SphygmoCor, AtCor). For HRQOL assessment the EQ5D instrument was utilized. EQ5D estimates five dimensions (mobility; self-care; usual activities; pain/discomfort; anxiety/depression) which are subdivided in three severity levels. These dimensions are transformed in an overall index, MVH-York-A1-tariff (0=worst, 1=best). Additionally, EQ5D involves a visual analogue scale (VAS) in which respondents self-rate their health state (0=worst, 100=best).

Results: A hundred and fifty consecutive subjects (80 males; 55±15 years old; BMI: 27.3±4.4 kg/m2, 49% hypertensives, 10% diabetics) were included in the study. Average brachial/ aortic SBP was 131±16/ 121±17 mmHg, DBP was 78±9/ 79±9 mmHg. Average AIx/ AIx75bpm was 28.8±14.6/ 23.3±14.3, AP/ AP@75bpm 13.2±8.1/ 9.8±6.7 mmHg. Mean MVH-York-A1-tariff was 0.85±0.18, while VAS was 78.3±13.6. Peripheral haemodynamics were correlated neither with MVH-York-A1-tariff nor with VAS. However, a negative correlation between aortic SBP, AIx, AIx@75, AP, AP@75 and HRQOL indices was observed (Table).

Conclusions: In the present study, aortic SBP, AIx and AP were found to negatively correlate with HRQOL.

HRQOL indices & haemodynamics
MVH York A1 tariff VAS
C.C. p C.C. p
Brachial SBP, mmHg 0,008 0,928 −0,099 0,238
Brachial DBP, mmHg 0,074 0,377 −0,103 0,218
Aortic SBP, mmHg −0,061 0,469 −0,193* 0,020
Aortic DBP, mmHg 0,078 0,348 −0,102 0,221
AIx −0,246** 0,003 −0,297** <0,001
AIx @75bpm −0,240** 0,004 −0,298** <0,001
AP, mmHg −0,218** 0,008 −0,299** <0,001
AP @75bpm, mmHg −0,199* 0,016 −0,298** <0,001

AIx: Augmentation Index; AP: Augmentation Pressure; CC: Correlation Coefficient; DBP: Diastolic Blood Pressure; MBP: Mean Blood Pressure; PWV: Pulse Wave Velocity; SBP: Systolic Blood Pressure level of significance:

*

0.05,

**

0.01

Open Access
This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
135 - 135
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.118How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - D.A. Vrachatis
AU  - A. Argyris
AU  - A. Papadopoulos
AU  - T.G. Papaioannou
AU  - E. Aissopou
AU  - G. Konstantonis
AU  - D. Niakas
AU  - P. Sfikakis
AU  - A. Protogerou
PY  - 2013
DA  - 2013/11/11
TI  - P3.31 CORRELATION OF CENTRAL HAEMODYNAMICS WITH HEALTH-RELATED QUALITY OF LIFE
JO  - Artery Research
SP  - 135
EP  - 135
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.118
DO  - 10.1016/j.artres.2013.10.118
ID  - Vrachatis2013
ER  -