Artery Research

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Volume 7, Issue 3-4, September 2013, Pages 123 - 123

P2.17 ECHOGENICITY OF THE COMMON CAROTID ARTERY INTIMA-MEDIA COMPLEX IN STROKE

Authors
K. Aizawa1, 2, S. Elyas1, 2, D.D. Adingupu1, 2, A.C. Shore1, 2, W.D. Strain1, 2, P.E. Gates1, 2
1University of Exeter Medical School, Exeter, United Kingdom
2NIHR Exeter Clinical Research Facility, Exeter, United Kingdom
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.078How to use a DOI?
Abstract

Introduction: Grey scale median of the carotid artery intima-media complex (IM-GSM) is a recently introduced measurement thought to reflect the composition of the arterial wall. Carotid artery intima-media thickness (IMT) has been shown to be a predictor of a future stroke incidence, but the relationship between IM-GSM and stroke is unclear. This study therefore examined IM-GSM in individuals with stroke.

Methods: Fifty-seven healthy individuals (CONTROL: 64.1±7.8yrs, 26F) and 96 individuals with cerebrovascular disease (either stroke or transient ischemic attack) diagnosed within 3 months before the study visit (CRVD: 68.6±9.8yrs, 30F) were included in this study. Common carotid artery diameter and far-wall IMT images were obtained using a Doppler ultrasound machine. IMT and IM-GSM were analyzed using semi-automated edge-detection software.

Results: Carotid diameter and IMT were greater in CRVD than CONTROL (all p<0.005). IM-GSM was significantly higher in CONTROL than CRVD (119.5±27.3au vs 105.8±30.3au, p<0.01). IMT and IM-GSM were similar between the carotid arteries of the affected and unaffected sides in CRVD. In a pooled data set, there was a significant reduction in IMT (r=−0.53) and wall-to-lumen ratio (WLR; r=−0.50) with the increase in the quartiles of IM-GSM (both p<0.001).

Conclusion: These results demonstrate that IM-GSM was lower in CRVD than CONTROL, and the level of IM-GSM appeared to be systemic in CRVD. The inverse association observed between IMT, WLR and IM-GSM may suggest an alteration in carotid artery wall composition with the degree of arterial remodelling.

Open Access
This is an open access article distributed under the CC BY-NC license.

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
123 - 123
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.078How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - K. Aizawa
AU  - S. Elyas
AU  - D.D. Adingupu
AU  - A.C. Shore
AU  - W.D. Strain
AU  - P.E. Gates
PY  - 2013
DA  - 2013/11/11
TI  - P2.17 ECHOGENICITY OF THE COMMON CAROTID ARTERY INTIMA-MEDIA COMPLEX IN STROKE
JO  - Artery Research
SP  - 123
EP  - 123
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.078
DO  - 10.1016/j.artres.2013.10.078
ID  - Aizawa2013
ER  -