P1.18 FEASIBILITY OF 24-HOUR PULSE WAVE VELOCITY ANALYSIS IN THE MANAGEMENT OF PATIENTS WITH RENAL TRANSPLANTATION

DOI

10.1016/j.artres.2013.10.049How to use a DOI?

Abstract

The aim of study was to assess the feasibility of 24-hour PWV analysis in management of patients with renal transplantation (RT). Overall, 41 patients were recruited from the transplant waiting list. All the measurements were performed before and at 1 and 20 weeks after RT. The Pulse Time Index of Norm (PTIN) defined as the percentage of 24-hour period during which the PWV does not exceed 10 m/second. Before RT, the mean PTIN was 56.3 (SD, 18.4). Then, a week after the RT, a decrease in PTIN was observed in most cases, going to 27.6 (SD, 11.1). After 20 weeks, the mean PTIN increased again to 52.0 (SD, 23.6). We found that the persistence of arterial stiffness disturbances after RT appears relatively predictable. We determined the cut-off value of PTIN that could predict the two states of PTIN: a state of improvement or a state of decline/without change. The cut-off value of PTIN at 45% had a sensitivity of 69%, specificity of 76%, and AUC of 0.65. The analysis of variance showed that in the group with initial PTIN of 45% or higher, the PTIN in the remote period after transplantation changed significantly (P<0.05), whereas in the group with an initial PTIN lower than 45%, there were no significant changes. Thus, the analysis of 24-hour pulse wave velocity in the management of patients with RT using PTIN is feasible. PTIN seems to give us an opportunity to optimize aggressive therapeutic approach to postoperative hypertension in patients with RT.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - I.E. Minyukhina
AU  - I.N. Posokhov
PY  - 2013
DA  - 2013/11/11
TI  - P1.18 FEASIBILITY OF 24-HOUR PULSE WAVE VELOCITY ANALYSIS IN THE MANAGEMENT OF PATIENTS WITH RENAL TRANSPLANTATION
JO  - Artery Research
SP  - 115
EP  - 115
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.049
DO  - 10.1016/j.artres.2013.10.049
ID  - Minyukhina2013
ER  -