Artery Research

Volume 26, Issue 1, March 2020, Pages 21 - 26

Real-world Accuracy of Transthoracic Echocardiography in Diagnosing Bicuspid Aortic Valve Morphology: A Single Center UK Experience

Authors
Oliver James Harrison1, 2, Abdul Badran1, 2, *, Amer Harky3, Daniel Muller1, Benoy N. Shah4, Sunil K. Ohri1
1Department of Cardiac Surgery, University Hospital Southampton, UK
2Institute of Developmental Sciences, University of Southampton, UK
3Department of Cardiothoracic Surgery, Liverpool Heart and Chest, Liverpool, UK
4Department of Echocardiography, University Hospital Southampton, UK
*Corresponding author. Email: a.badran@nhs.net
Corresponding Author
Abdul Badran
Received 13 December 2019, Accepted 19 December 2019, Available Online 20 January 2020.
DOI
10.2991/artres.k.191219.001How to use a DOI?
Keywords
Aortic valve morphology; transthoracic echocardiography; bicuspid aortic valve
Abstract

Objectives: The aim of this study was to compare the diagnostic accuracy of Transthoracic Echocardiography (TTE) in assessing Bicuspid Aortic Valve (BAV) morphology.

Methods: Case notes of 408 patients (>18 years old) undergoing elective Aortic Valve (AV) surgery over a 2-year period were retrospectively reviewed. Aortic valve data was collected from preoperative TTE reports and intraoperative records. The diagnostic accuracy of TTE for identifying AV morphology was assessed using intraoperative findings as the gold standard. One-hundred-and-eighty-nine (46.3%) patients had a recent TTE with complete morphological assessment of the AV and an operation note documenting AV morphology. Cases that were ‘unable to be determined’ on TTE were included as false negatives.

Results: TTE correctly identified AV morphology in 165 of the patients, equating to an accuracy of 79.1% (sensitivity = 72.4%, specificity = 87.3%). For BAV patients alone, accuracy was 81.3% (sensitivity = 65.8%, specificity = 90.0%), and for Tricuspid Aortic Valve (TAV) patients, accuracy was 77.1% (sensitivity = 75.5%, specificity = 81.4%). There was no significant difference in diagnostic accuracy of TTE for BAV and TAV (p = 0.464), nor was there any difference between valve calcification (p = 0.196) and functional disease (p = 0.088).

Conclusion: Our data suggests that identification of BAV from TTE requires expertise and therefore it is operator dependent. A larger study is required to confirm our findings.

Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
26 - 1
Pages
21 - 26
Publication Date
2020/01/20
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191219.001How to use a DOI?
Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Oliver James Harrison
AU  - Abdul Badran
AU  - Amer Harky
AU  - Daniel Muller
AU  - Benoy N. Shah
AU  - Sunil K. Ohri
PY  - 2020
DA  - 2020/01/20
TI  - Real-world Accuracy of Transthoracic Echocardiography in Diagnosing Bicuspid Aortic Valve Morphology: A Single Center UK Experience
JO  - Artery Research
SP  - 21
EP  - 26
VL  - 26
IS  - 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191219.001
DO  - 10.2991/artres.k.191219.001
ID  - Harrison2020
ER  -