4.6 RELATIONSHIP OF CAROTID ARTERIAL FUNCTIONAL AND STRUCTURAL CHANGES TO LEFT ATRIAL VOLUME INUNTREATED HYPERTENSION

Joanna Jaroch*; Barbara Rzyczkowska; Zbigniew Bociaga; Olga Vriz; Caterina Driussi; Maria Loboz-Rudnicka; Krzysztof Dudek; Krystyna Loboz-Grudzien

doi:10.1016/j.artres.2015.10.025

<Previous Article In Issue

Next Article In Issue>

Volume 12, Issue C, December 2015, Pages 45 - 45

4.6 RELATIONSHIP OF CAROTID ARTERIAL FUNCTIONAL AND STRUCTURAL CHANGES TO LEFT ATRIAL VOLUME INUNTREATED HYPERTENSION

Authors

Joanna Jaroch*¹, Barbara Rzyczkowska¹, Zbigniew Bociaga¹, Olga Vriz¹, Caterina Driussi³, Maria Loboz-Rudnicka¹, Krzysztof Dudek⁴, Krystyna Loboz-Grudzien¹^{, 2}

¹T.Marciniak Hospital, Department of Cardiology, Wroclaw, Poland

²Wroclaw Medical University; Health Science Faculty, Wroclaw, Poland

³Division of Cardiology, San Antonio Hospital, San Daniele del Friuli, Udine, Italy

⁴Institute of Machine Design and Operation, Technical University of Wroclaw, Wroclaw, Poland

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.025 How to use a DOI?
Abstract: The contribution of arterial functional and structural changes to left ventricular (LV) diastolic dysfunction has been the area of latest research. There are some studies on the relationship of arterial stiffness (a.s.) and left atrial (LA) remodeling as a marker of diastolic burden. Little is known on the association of arterial structural changes and LA remodeling in hypertension (H).

The aim of this study was to examine the relationship of carotid a.s. and intimamedia thickness (IMT) to LA volume in subjects with H.

The study included 245 previously untreated hypertensives (166 women and 79 men, mean age 53.7 ± 11.8 years). Each patient was subjected to echocardiography with measurement of LA volume, evaluation of left ventricular hypertrophy (LVH) and LV systolic/diastolic function indices, integrated assessment of carotid IMT and echotracking of a.s. and wave reflection parameters.

Results: The following parameters were identified as independent determinants of indexed LA volume on multivariate regression analysis: diastolic blood pressure (beta = −0.229, p < 0.001), left ventricular mass index (LVMI; beta = 0.258, p < 0.001), E/e′ index (ratio of early mitral flow wave velocity - E to early diastolic mitral annular velocity-e′; beta = 0.266, p = 0.001), augmentation index (AI; beta = 0.143, p = 0.008) and bodymass index (BMI; beta = 0.132, p = 0.017). No correlations between indexed LA volume and IMT were found.

Conclusion: There is a significant relationship of carotid arterial stiffness but not intima-media thickness to LA volume in patients with untreated hypertension.
Open Access: This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

<Previous Article In Issue

Next Article In Issue>

Journal: Artery Research
Volume-Issue: 12 - C
Pages: 45 - 45
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.025 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Joanna Jaroch*
AU  - Barbara Rzyczkowska
AU  - Zbigniew Bociaga
AU  - Olga Vriz
AU  - Caterina Driussi
AU  - Maria Loboz-Rudnicka
AU  - Krzysztof Dudek
AU  - Krystyna Loboz-Grudzien
PY  - 2015
DA  - 2015/11/23
TI  - 4.6 RELATIONSHIP OF CAROTID ARTERIAL FUNCTIONAL AND STRUCTURAL CHANGES TO LEFT ATRIAL VOLUME INUNTREATED HYPERTENSION
JO  - Artery Research
SP  - 45
EP  - 45
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.025
DO  - 10.1016/j.artres.2015.10.025
ID  - Jaroch*2015
ER  -

download .riscopy to clipboard