Artery Research

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Volume 12, Issue C, December 2015, Pages 35 - 35

P8.6 PULSATILE COMPONENT OF CENTRAL BLOOD PRESSURE AND THE RISK OF STROKE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY

Authors
Piotr Jankowski*, Agnieszka Bednarek, Malgorzata Kloch-Badelek, Magdalena Loster, Leszek Bryniarski, Kalina Kawecka-Jaszcz, Danuta Czarnecka
Jagiellonian University, 1st Department of Cardiology, Interventional Electrocardiology and Hypertension, Krakow, Poland
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.328How to use a DOI?
Abstract

Background: There is ongoing debate concerning the best blood pressure (BP) parameter predicting cardiovascular risk. The aim of the analysis was to investigate the relationship between central BP and stroke in patients undergoing coronary angiography.

Methods: The study group consisted of 954 patients (691 men and 263 women; mean age: 57.3±10.0 years) undergoing coronary angiography with left ventricular EF≥40%. A vast majority of participants was prescribed BP-lowering drugs. Invasive ascending aortic BP during catheterization was taken at baseline. The duration of follow-up was 53.4±18.8 months. We defined pulsatility as the ratio of pulse pressure to mean BP. The Cox proportional hazard regression analysis was used to assess the relation between BP-derived indices and the risk of stroke.

Results: During the follow-up 19 (2.0%) patients suffered from stroke and 57 (6.0%) from stroke or CV death. The multivariate hazard ratios related to BP-derived indices according to the presence of HT are given in the table.

BP – related variables Stroke CV death or stroke
Systolic blood pressure per SD 1.32(0.85–2.04) 1.05(0.79–1.38)
Diastolic blood pressure per SD 0.88(0.57–1.36) 0.80(0.61–1.05)
Mean blood pressure per SD 1.08(0.71–1.64) 0.91(0.70–1.19)
Pulse pressure per SD 1.65(1.03–2.66) 1.25(0.93–1.67)
Pulsatility per SD 2.07(1.25–3.42) 1.50(1.11–2.03)

Conclusion: Pulsatile, but not steady component of central blood pressure predicts the risk of stroke in coronary patients.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
35 - 35
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.328How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Piotr Jankowski*
AU  - Agnieszka Bednarek
AU  - Malgorzata Kloch-Badelek
AU  - Magdalena Loster
AU  - Leszek Bryniarski
AU  - Kalina Kawecka-Jaszcz
AU  - Danuta Czarnecka
PY  - 2015
DA  - 2015/11/23
TI  - P8.6 PULSATILE COMPONENT OF CENTRAL BLOOD PRESSURE AND THE RISK OF STROKE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY
JO  - Artery Research
SP  - 35
EP  - 35
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.328
DO  - 10.1016/j.artres.2015.10.328
ID  - Jankowski*2015
ER  -