Artery Research

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Volume 12, Issue C, December 2015, Pages 37 - 37

P8.15 THE RELATION BETWEEN ARTERIAL STIFFNESS-RELATED, AND STEADY BLOOD PRESSURE COMPONENTS AND LEFT ATRIAL VOLUME IN THE CONTEXT OF LEFT VENTRICULAR MASS INDEX

Authors
Marta Rojek1, 2, Jerzy Gasowski*3, Marek Rajzer1, Tomasz Pizon4, Danuta Czarnecka1
11st Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Cracow, Poland
2Medical Faculty, Dresden University of Technology, Dresden, Germany
3Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Cracow, Poland
4Department of Observational and Internal Medicine, University Hospital, Cracow, Poland
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.337How to use a DOI?
Abstract

Objective: To check of relation between blood pressure (BP) and arterial stiffness parameters and measures of left atrial volume to verify whether it is the arterial stiffness-related BP parameters or mean arterial pressure (MAP)that could be responsible for increase in risk of atrial fibrillation.

Methods: Group of Cracow suburban area inhabitants (n=205, 66% women) was examined for: 24h(SBP24h, DBP24h, MAP24h, PP24h), central(cSBP, cDBP, cMAP, cPP) BPs, carotid-femoral pulse wave velocity (PWV), parameters of left ventricular mass (LVM, LVMI) and left atrial volume (LAV, LAVI). Anthropometric and clinical data were gathered via questionnaire. With division according to sex-stratified dichotomised LVMI (97g/m2 for women, 110g/m2 for men), correlation analysis was performed and further linear regression models were fitted to identify and assess respective value of steady and pulsatile BP components as factors related to left atrial volume measures.

Results: After subdivision of population, statistically significant correlations (p < 0,05) were identified only in persons below group-median value of LVMI. For LAV:SBP24h(r=0,26), MAP24h(r=0,16), PP24h(r=0,28), cSBP(r=0,33), cDBP(r=0,29), cMAP(r=0,34), cPP(r=0,2), PWV(r=0,25). For LAVI:SBP24h(r=0,24), PP24h(r=0,28), cSBP(r=0,34), cDBP(r=0,30), cMAP(r=0,32), cPP(r=0,25), PWV(r=0,28). In regression analysis, only MAP from 24h and pulse wave analysis, relates to left atrial volume, in persons below LVMI group-median value (p< 0,05). For LAV: cMAP(β=0,35), MAP24h(β=0,35). For LAVI:cMAP(β=0,13). In persons with increase in LVMI no relation between BP and PWV and left atrial volume was found.

Conclusions: Mean arterial pressure is associated with greater left atrial volumes. The fact that relation is blunted in persons with greater LVMI, itself related more to MAP, shows importance of this particular form of target organ damage in relation to LAV.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
37 - 37
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.337How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Marta Rojek
AU  - Jerzy Gasowski*
AU  - Marek Rajzer
AU  - Tomasz Pizon
AU  - Danuta Czarnecka
PY  - 2015
DA  - 2015/11/23
TI  - P8.15 THE RELATION BETWEEN ARTERIAL STIFFNESS-RELATED, AND STEADY BLOOD PRESSURE COMPONENTS AND LEFT ATRIAL VOLUME IN THE CONTEXT OF LEFT VENTRICULAR MASS INDEX
JO  - Artery Research
SP  - 37
EP  - 37
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.337
DO  - 10.1016/j.artres.2015.10.337
ID  - Rojek2015
ER  -