P7.17 DISASSOCIATION OF BLOOD PRESSURE FROM AORTIC RESERVOIR CHARACTERISTICS BETWEEN THE AORTA AND RADIAL ARTERIES

Xiaoqing Peng*; Martin Schultz; Justin Davies; Dean Picone; Andrew Black; Nathan Dwyer; Phil Roberts-Thomson; James Sharman

doi:10.1016/j.artres.2015.10.320

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Volume 12, Issue C, December 2015, Pages 33 - 34

P7.17 DISASSOCIATION OF BLOOD PRESSURE FROM AORTIC RESERVOIR CHARACTERISTICS BETWEEN THE AORTA AND RADIAL ARTERIES

Authors

Xiaoqing Peng*¹, Martin Schultz¹, Justin Davies², Dean Picone¹, Andrew Black³, Nathan Dwyer³, Phil Roberts-Thomson³, James Sharman¹

¹Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia

²International Centre for Circulatory Health, Imperial College, London, W2 1LA, UK

³Royal Hobart Hospital, Hobart, TAS, Australia

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.320 How to use a DOI?
Abstract: Background: Aortic reservoir pressure (RP) and excess pressure (XSP) predict cardiovascular events independent of clinic blood pressure (BP). It is unknown whether RP and XSP change in magnitude from the central to peripheral large arteries where conventional BP is measured. This information has implications for understanding the arterial pathophysiology. This study aimed to determine the change in RP and XSP from the aorta to the brachial and radial arteries, as well as associations of these indices with BP.

Methods: 23 participants (aged 65±9 years, 70% male) undergoing clinically indicated cardiac angiography had intra-arterial pressure waveforms measured via fluid-filled catheter in the ascending aorta, brachial (mid-humorous) and radial arteries (wrist) by catheter pull-back. RP and XSP (using previously published algorithms), and BP were derived from pressure waveforms at each location.

Results: There was a non-significant decrease in RP from the aorta to the brachial and radial arteries (112±22, 109±18, 103±17 mmHg respectively, p=0.242). On the other hand, XSP significantly increased from the aorta to the brachial and radial arteries (21±8, 41±15, 58±19 mmHg respectively, p<0.001). However, neither RP or XSP (either measured by peak or integral) were significantly associated with either systolic BP or pulse pressure at any arterial location (p>0.05 all).

Conclusion: RP is relatively constant between the aorta and radial arteries, whereas XSP increases significantly. Neither indices are related to BP, thus supporting the independent pathophysiological relevance of aortic reservoir characteristics.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 33 - 34
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.320 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Xiaoqing Peng*
AU  - Martin Schultz
AU  - Justin Davies
AU  - Dean Picone
AU  - Andrew Black
AU  - Nathan Dwyer
AU  - Phil Roberts-Thomson
AU  - James Sharman
PY  - 2015
DA  - 2015/11/23
TI  - P7.17 DISASSOCIATION OF BLOOD PRESSURE FROM AORTIC RESERVOIR CHARACTERISTICS BETWEEN THE AORTA AND RADIAL ARTERIES
JO  - Artery Research
SP  - 33
EP  - 34
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.320
DO  - 10.1016/j.artres.2015.10.320
ID  - Peng*2015
ER  -

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