Artery Research

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Volume 12, Issue C, December 2015, Pages 25 - 25

P6.4 PLATELET ACTIVITY IN TEENAGE BOYS WITH PRIMARY ARTERIAL HYPERTENSION

Authors
Indre Bauziene*1, Kazys Simanauskas1, Virginijus Sapoka1, Vytautas Kasiulevicius1, Reda Matuzeviciene1, Kristina Ryliskiene1, Augustina Jankauskiene1, Tomas Rekasius2
1Faculty of Medicine, Vilnius University, Vilnius, Lithuania
2Department of Mathematical Statistics, Gediminas Technical University, Vilnius, Lithuania
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.288How to use a DOI?
Keywords
primary arterial hypertension; platelet activity
Abstract

Objective: Primary arterial hypertenion for teen has caused a lot of debate today, there is too much uncertainty about platelet functional changes in patients with PAH. The objective was to evaluate platelet activity in healthy and suffering from PAH groups of 17–18 year old boys.

Materials and methods: Platelet functional activity was determined by flow cytometry. Platelets used to identify the three antibodies: CD42a (GP IX), CD41a (GP IIb) and CD61 (GP IIIa) and assessing the activity of select PAC-1 antibody that binds specifically to activated GPIIb / IIIa complex. Through 2008–2013 years platelet activity was assessed 38 PAH 17–18 year-old boys (case group) and 41 healthy the same age teenager (control group). A statistical analysis was done and the significance assessed by a X-square test. The statistical difference was considered significant if the p value was below 0.05.

Results: In PAH group of teen boys were not found statistically significantly more PAC-1 antibody attaghed platelets. Based on the results of this study we could argue that the platelet functional activity of PAH teens is not higher than in healthy adolescents.

Conclusions: PAH teen platelet functional activity does not differ from healthy peers. To obtain accurate results, it should be performed at a higher sample survey.

Open Access
This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
25 - 25
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.288How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Indre Bauziene*
AU  - Kazys Simanauskas
AU  - Virginijus Sapoka
AU  - Vytautas Kasiulevicius
AU  - Reda Matuzeviciene
AU  - Kristina Ryliskiene
AU  - Augustina Jankauskiene
AU  - Tomas Rekasius
PY  - 2015
DA  - 2015/11/23
TI  - P6.4 PLATELET ACTIVITY IN TEENAGE BOYS WITH PRIMARY ARTERIAL HYPERTENSION
JO  - Artery Research
SP  - 25
EP  - 25
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.288
DO  - 10.1016/j.artres.2015.10.288
ID  - Bauziene*2015
ER  -