Artery Research

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Volume 12, Issue C, December 2015, Pages 28 - 28

P6.14 THE EFFECT OF PHYSICAL ACTIVITY ON 24-HOUR AUGMENTATION INDEX

Authors
Niamh Chapman*1, James Thomas1, Maria Kearney1, Laura Watkeys1, Margaret Munnery2, John R. Cockcroft2, Carmel M. McEniery3, Eric J. Stohr1, Barry J. McDonnell1
1Cardiff Metropolitan University, Cardiff, UK
2Wales Heart Research Institute, Cardiff University, Cardiff, UK
3Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.298How to use a DOI?
Abstract

Introduction: Augmentation Index (AIx) is a surrogate measure of systemic arterial stiffness and wave reflections. Clinic measures of AIx are considered to be a sensitive measure of risk in young adults and are lower in individuals who take part in high levels of physical activity (PA). The development of an ambulatory blood pressure monitoring (ABPM) system, which also calculates AIx, now allows usual AIx to be assessed. The aim of this study was to assess the association between 24-hour AIx and levels of physical activity in a young healthy cohort.

Methods: Forty-six adults (23±5years, 28% male) took part in the study. 24-hour AIx@75 (AIx at heart rate 75bpm) was measured using the ABPM device (Mobil-O-Graph, IEM). Weekly PA levels were recorded using a detailed PA questionnaire (total minutes per week).

Results: An inverse association between 24-hour AIx@75, Night-time AIx@75 and levels of PA (r =−0.420, P<0.01 and r =−0.403, P<0.01, respectively) were observed. Interestingly, no associations were observed between 24-hour blood pressure and levels of PA.

Conclusion: These novel data, in a young normotensive cohort illustrate the beneficial effect of increased PA on 24-hour AIx. 24-hour measurements of vascular function may provide a more robust tool to understand the chronic effects of PA on vascular health. Further studies are needed to understand the use of ABPM for 24-hour monitoring of vascular stiffness.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
28 - 28
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.298How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Niamh Chapman*
AU  - James Thomas
AU  - Maria Kearney
AU  - Laura Watkeys
AU  - Margaret Munnery
AU  - John R. Cockcroft
AU  - Carmel M. McEniery
AU  - Eric J. Stohr
AU  - Barry J. McDonnell
PY  - 2015
DA  - 2015/11/23
TI  - P6.14 THE EFFECT OF PHYSICAL ACTIVITY ON 24-HOUR AUGMENTATION INDEX
JO  - Artery Research
SP  - 28
EP  - 28
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.298
DO  - 10.1016/j.artres.2015.10.298
ID  - Chapman*2015
ER  -