P5.17 CAROTID PULSE PRESSURE ASSESSMENT BY MEANS OF AN ACCELEROMETRIC SENSOR

DOI

10.1016/j.artres.2015.10.280How to use a DOI?

Abstract

Central pulse pressure (cPP) is increasingly investigated as possible independent predictor of cardiovascular risk and carotid pulse pressure (carPP) can be used as a surrogate marker of cPP. Despite its importance, carPP measurement remains challenging in clinical practice. The aim of this study was to introduce a new easier-to-use method for non-invasive carPP evaluation based on an accelerometric sensor.

Accelerometric signals were recorded in 22 subjects (males: 45.5%, 47.4±17 years, hypertension: 50%; smoking: 18%; diabetes: 23%; hypercholesterolemia: 27%). Under the hypothesis that these signals represent the acceleration linked to the displacement of the carotid near wall, carPP_acc values were achieved double integrating the accelerometric waveforms and calibrating the obtained diameter curves with brachial pressure measurements. carPP_acc measurements were compared with tonometric assessments (carPP_ton). Moreover, accelerometric carotid pressure waveforms (P_acc) were contrasted in terms of shape to those obtained by tonometry (P_ton), calculating the root mean square error (RMSE_ton) and the regression coefficients (r_ton).

carPP_acc values (46±10.55 mmHg) were significantly correlated with carPP_ton (47.5±11.2 mmHg) assessments (R=0.93, p<0.001). The Bland-Altman analysis provided a non-significant bias of −1.54 mmHg. The validity of the accelerometric approach was confirmed by morphological parameters (RMSE_ton=5±1.95 mmHg; r_ton=0.94±0.04).

In conclusion, carPP values obtained with the accelerometric device are in good correlation with those calculated with standard applanation tonometry. Therefore, the proposed approach, providing an easier and more available measurement, could represent a valid alternative to existing and used technique for carPP assessment.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - Nicole Di Lascio*
AU  - Vincenzo Gemignani
AU  - Rosa Maria Bruno
AU  - Elisabetta Bianchini
AU  - Francesco Stea
AU  - Lorenzo Ghiadoni
AU  - Francesco Faita
PY  - 2015
DA  - 2015/11/23
TI  - P5.17 CAROTID PULSE PRESSURE ASSESSMENT BY MEANS OF AN ACCELEROMETRIC SENSOR
JO  - Artery Research
SP  - 23
EP  - 24
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.280
DO  - 10.1016/j.artres.2015.10.280
ID  - DiLascio*2015
ER  -